Recent advances in polymeric transdermal drug delivery systems

F Sabbagh, BS Kim - Journal of controlled release, 2022 - Elsevier
Transdermal delivery has proven to be one of the most favorable methods among novel
drug delivery systems. Since drugs administered by transdermal delivery systems avoid the …

Zero-order drug delivery: State of the art and future prospects

ML Laracuente, HY Marina, KJ McHugh - Journal of Controlled Release, 2020 - Elsevier
Pharmaceutical drugs are an important part of the global healthcare system, with some
estimates suggesting over 50% of the world's population takes at least one medication per …

Review on rubbers in medicine: Natural, silicone and polyurethane rubbers

A Rahimi, A Mashak - Plastics, rubber and composites, 2013 - journals.sagepub.com
Natural, silicone and polyurethane rubbers are considered as three important biomaterials
which have found widespread applications in medical technology. Biocompatibility …

Advances in microbicide vaginal rings

RK Malcolm, KL Edwards, P Kiser, J Romano, TJ Smith - Antiviral research, 2010 - Elsevier
Vaginal ring devices capable of providing sustained/controlled release of incorporated
actives are already marketed for steroidal contraception and estrogen replacement therapy …

Microbicide vaginal rings: Technological challenges and clinical development

RK Malcolm, PJ Boyd, CF McCoy, DJ Murphy - Advanced drug delivery …, 2016 - Elsevier
Vaginal rings (VRs) are flexible, torus-shaped, polymeric devices designed to sustain
delivery of pharmaceutical drugs to the vagina for clinical benefit. Following first report in a …

Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings

RK Malcolm, AD Woolfson, CF Toner… - Journal of …, 2005 - academic.oup.com
Objectives: The feasibility of providing prolonged and controlled release of the experimental
non-nucleoside reverse transcriptase inhibitor TMC120 from a silicone vaginal ring in …

Development of long-acting bioadhesive vaginal gels of oxybutynin: Formulation, in vitro and in vivo evaluations

F Tuğcu-Demiröz, F Acartürk, D Erdoğan - International journal of …, 2013 - Elsevier
Overactive bladder (OAB) and vaginal dryness are common problems after menopause.
Oxybutynin (OXY) is an antimuscarinic agent that has been available for more than 30 years …

[图书][B] Enhancement in drug delivery

E Touitou, BW Barry - 2006 - taylorfrancis.com
Providing a significant cross-fertilization of ideas across several disciplines, Enhancement in
Drug Delivery offers a unique comprehensive review of both theoretical and practical …

[PDF][PDF] State of the art in intravaginal ring technology for topical prophylaxis of HIV infection

PF Kiser, TJ Johnson, JT Clark - Aids Rev, 2012 - researchgate.net
There is renewed interest in the development of long-term, controlled-release dosage forms
for the intravaginal delivery of antiretrovirals for HIV prophylaxis. This interest has catalyzed …

A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of action

SM Fetherston, P Boyd, CF McCoy, MC McBride… - European journal of …, 2013 - Elsevier
Vaginal rings are currently being developed for the long-term (at least 30days) continuous
delivery of microbicides against human immunodeficiency virus (HIV). Research to date has …