The thalamic reticular nucleus: a functional hub for thalamocortical network dysfunction in schizophrenia and a target for drug discovery

JA Pratt, BJ Morris - Journal of Psychopharmacology, 2015 - journals.sagepub.com
The thalamus (comprising many distinct nuclei) plays a key role in facilitating sensory
discrimination and cognitive processes through connections with the cortex. Impaired …

Thalamo-cortical communication, glutamatergic neurotransmission and neural oscillations: A unique window into the origins of ScZ?

J Pratt, N Dawson, BJ Morris, T Grent, F Roux… - Schizophrenia …, 2017 - Elsevier
The thalamus has recently received renewed interest in systems-neuroscience and
schizophrenia (ScZ) research because of emerging evidence highlighting its important role …

[HTML][HTML] 16p11 duplication disrupts hippocampal-orbitofrontal-amygdala connectivity, revealing a neural circuit endophenotype for schizophrenia

GC Bristow, DM Thomson, RL Openshaw, EJ Mitchell… - Cell reports, 2020 - cell.com
Summary Chromosome 16p11. 2 duplications dramatically increase risk for schizophrenia,
but the mechanisms remain largely unknown. Here, we show that mice with an equivalent …

[PDF][PDF] The thalamic reticular nucleus: A functional hub for thalamocortical network

JA Pratt, BJ Morris - drugs - core.ac.uk
The thalamus (comprising many distinct nuclei) plays a key role in facilitating sensory
discrimination and cognitive processes through connections with the cortex. Impaired …