Psychological stress is a crucial factor in the development of many skin diseases, and the
stigma caused by skin disorders may further increase the psychological burden, forming a …

Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …

The human gut microbiome contains the largest number of bacteria in the body and has the
potential to greatly influence metabolism, not only locally but also systemically. There is an …

The enteric nervous system is largely autonomous, and the central nervous system is
compartmentalized behind the blood-brain barrier. Yet the intestinal microbiota shapes gut …

Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

Glial cells have been proposed as a source of neural progenitors, but the mechanisms
underpinning the neurogenic potential of adult glia are not known. Using single cell …

Psychological stress and its sequelae pose a major challenge to public health. Immune
activation is conventionally thought to aggravate stress-related mental diseases such as …

Enteric glia are the partners of neurons in the enteric nervous system throughout the
gastrointestinal tract. Roles fulfilled by enteric glia are diverse and contribute to maintaining …

The brain and gut are intricately connected and respond to various stimuli. Stress-induced
brain-gut communication is implicated in the pathogenesis and relapse of gut disorders. The …

The term “immune-mediated inflammatory diseases (IMIDs)” refers to several inflammatory
pathologies of multifactorial etiology and involving either simultaneously or sequentially …