In recent years, much new data on intestinal alkaline phosphatase (IAP) have been
published, and major breakthroughs have been disclosed. The aim of the present review is …

Importance Sepsis-associated acute kidney injury (AKI) adversely affects long-term kidney
outcomes and survival. Administration of the detoxifying enzyme alkaline phosphatase may …

Background: Intestinal alkaline phosphatase (IAP) as a tissue-specific isozyme of alkaline
phosphatases is predominantly produced by enterocytes in the proximal small intestine. In …

Abstract The lipopolysaccharide (LPS)–toll-like receptor-4 (TLR4) pathway plays an
important role in liver failure. Recombinant alkaline phosphatase (recAP) deactivates LPS …

Sepsis is a life-threatening inflammatory syndrome accompanying a bloodstream infection.
Frequently secondary to pathogenic bacterial infections, sepsis remains difficult to treat as a …

Alkaline phosphatase (AP) is a ubiquitous membrane–bound glycoprotein that catalyzes
phosphate monoesters' hydrolysis from organic compounds, an essential process in cell …

Acute kidney injury (AKI) is associated with prolonged hospitalization and mortality following
infant cardiac surgery, but therapeutic options are limited. Alkaline phosphatase (AP) …

Alkaline phosphatase (ALP) is abundant in raw milk. Because of its high heat resistance,
ALP negative is used as an indicator of successful sterilization. However, pasteurized milk …

While serum alkaline phosphatase activity has become a routine clinical measurement, we
have found that physicians' knowledge of the pathophysiology of this enzyme is almost …

Abstract Background and Objective Previous clinical trials have suggested that bovine
intestinal alkaline phosphatase has renal protective effects in patients with sepsis …