Serotonin (5‐HT) induces concentration‐dependent metabolic effects in diverse cell types,
including neurons, entherochromaffin cells, adipocytes, pancreatic beta‐cells, fibroblasts …

The present review summarizes the data concerning the influence of serotonin (5-HT)
receptors on body temperature in warm-blooded animals and on processes associated with …

5-hydroxytryptamine type 3 (5-HT3) receptors are ligand gated ion channels, which clearly
distinguish their mode of action from the other G-protein coupled 5-HT or serotonin …

Methods Samples from ascending, transverse, descending, and sigmoid human colon were
dissected into 3 separate layers (mucosa, longitudinal, and circular muscles) and ileum …

Factors underlying individual vulnerability to develop alcoholism are largely unknown. In
humans, the risk for alcoholism is associated with elevated cue reactivity. Recent evidence …

Spinal cord injury (SCI) often leads to defecation dysfunction. Sacral nerve electrical
stimulation (SNS) therapy could improve defecation function. The present study aimed to …

Chemotherapy-induced nausea and vomiting (CINV) is associated with distressing adverse
effects observed in patients during cytotoxic chemotherapy. One of the potential factors …

5-HT3 receptor antagonists corresponding to ondansetron, granisetron, tropisetron, and
palonosetron are clinically accustomed to treating nausea and emesis in chemotherapy …

Chemotherapy-induced nausea and vomiting is one of the most concerning adverse drug
effects from cytotoxic chemotherapy. Despite appropriate use of antiemetic guidelines, 20 …

Abstract Serotonin type 3 (5-hydroxytrptamine-3, 5-HT 3) receptors are ligand-gated cation
channels present in both central and peripheral nervous systems. In humans there are five …