Anticancer activity of complexes of the third row transition metals, rhenium, osmium, and iridium

CC Konkankit, SC Marker, KM Knopf, JJ Wilson - Dalton Transactions, 2018 - pubs.rsc.org
The clinical success of the platinum-based chemotherapeutic agents has prompted the
investigation of coordination and organometallic complexes of alternative metal centers for …

Protective effects of Vitis vinifera (grapes) and one of its biologically active constituents, resveratrol, against natural and chemical toxicities: A comprehensive review

J Tabeshpour, S Mehri… - Phytotherapy …, 2018 - Wiley Online Library
Vitis vinifera (grape) is one of the “most‐produced fruit” in the world. Grape seeds are a
valuable source of phenolic compounds including resveratrol (RSV). Grape and one of its …

Conventional and microwave-assisted synthesis, anticancer evaluation, 99mTc-coupling and In-vivo study of some novel pyrazolone derivatives

BM Essa, AA Selim, GH Sayed, KE Anwer - Bioorganic Chemistry, 2022 - Elsevier
New pyrazolone derivatives were successfully synthesized by both microwave-assisted and
conventional techniques. Compound 3 (3-(3-Methyl-5-oxo-4, 5-dihydro-1H-pyrazol-1-yl)-3 …

Synthesis, characterization, radiolabeling and biodistribution of a novel cyclohexane dioxime derivative as a potential candidate for tumor imaging

MA Motaleb, AA Selim, M El-Tawoosy… - … journal of radiation …, 2018 - Taylor & Francis
Purpose: Dioxime derivative is reported to exhibit high affinity towards tumor cells. The
objective of the present study is to synthesize a new dioxime derivative to be labeled with …

Preparation, characterization and evaluation of [125I]-pirarubicin: a new therapeutic agent for urinary bladder cancer with potential for use as theranostic agent

OA El-Kawy, G Abdelaziz - Applied Radiation and Isotopes, 2022 - Elsevier
Improving urinary bladder cancer diagnosis, follow-up, and therapy tools to overcome
existing limitations and increase survival rates is a highly desirable goal. In the current …

Radiolabeling of graphene oxide by Tchnetium-99m for infection imaging in rats

SB Challan, A Massoud - Journal of Radioanalytical and Nuclear …, 2017 - Springer
Graphene oxide (GO) was synthesized by modified Hummers method and was
characterized using HR-TEM, FTIR, XRD and zeta potential. The antibacterial activity of GO …

Bulk production and evaluation of high specific activity 186gRe for cancer therapy using enriched 186WO3 targets in a proton beam

T Mastren, V Radchenko, HT Bach, ER Balkin… - Nuclear Medicine and …, 2017 - Elsevier
Abstract Introduction Rhenium-186g (t 1/2= 3.72 d) is a β− emitting isotope suitable for
theranostic applications. Current production methods rely on reactor production by way of …

Discovery and design of radiopharmaceuticals by in silico methods

M Salahinejad, DA Winkler… - Current …, 2022 - ingentaconnect.com
There has been impressive growth in the use of radiopharmaceuticals for therapy, selective
toxic payload delivery, and noninvasive diagnostic imaging of disease. The increasing …

99mTc-roxifiban: a potential molecular imaging agent for the detection and localization of acute venous thrombosis

OA El-Kawy, JA García-Horsman - Journal of Radioanalytical and Nuclear …, 2017 - Springer
Abstract 99m Tc-roxifiban was obtained in a high radiochemical yield (98.4%) by
complexing~ 750 MBq 99m Tc with 2.5 mg roxifiban in the presence of 150 µg SnCl 2· 2H 2 …

99mTc-labeled glimepiride as a tracer for targeting pancreatic β-cells mass: preparation and preclinical evaluation

OA El-Kawy, JA García-Horsman - Journal of Radioanalytical and Nuclear …, 2017 - Springer
Complexation of glimepiride with 99m Tc, factors affecting yield and suitability of the 99m Tc-
glimepiride as a tracer for pancreatic β-cells mass were investigated. The radiocomplex …