Synthetic or food-derived vitamin C—are they equally bioavailable?

AC Carr, MCM Vissers - Nutrients, 2013 - mdpi.com
Vitamin C (ascorbate) is an essential water-soluble micronutrient in humans and is obtained
through the diet, primarily from fruits and vegetables. In vivo, vitamin C acts as a cofactor for …

Regulatory effects of Cu, Zn, and Ca on Fe absorption: the intricate play between nutrient transporters

N Scheers - Nutrients, 2013 - mdpi.com
Iron is an essential nutrient for almost every living organism because it is required in a
number of biological processes that serve to maintain life. In humans, recycling of senescent …

Urate and its transgenic depletion modulate neuronal vulnerability in a cellular model of Parkinson's disease

S Cipriani, CA Desjardins, TC Burdett, Y Xu, K Xu… - PloS one, 2012 - journals.plos.org
Urate is a major antioxidant as well as the enzymatic end product of purine metabolism in
humans. Higher levels correlate with a reduced risk of developing Parkinson's disease (PD) …

Hormonal therapy of intrinsic aging

CC Zouboulis, E Makrantonaki - Rejuvenation research, 2012 - liebertpub.com
Intrinsic skin aging represents the biological clock of the skin cells per se and reflects the
reduction processes that are common in internal organs. The reduced secretion of the …

[PDF][PDF] Bioavailability and Bioactivity of Vitamin CA Review.

EDY SUBROTO, NURAG PUTRI… - International Journal …, 2021 - researchgate.net
Vitamin C is a water-soluble vitamin and acts as an antioxidant and free radical scavenger,
which can be used as one of the cheapest drugs that can protect humans from infection …

Iron transport through ferroportin is induced by intracellular ascorbate and involves IRP2 and HIF2α

N Scheers, AS Sandberg - Nutrients, 2014 - mdpi.com
A few tightly regulated transport proteins mediate iron absorption across the intestinal
epithelium. At the basolateral border of intestinal cells there is one identified transporter …

Development of the Caco-2 model for assessment of iron absorption and utilisation at supplemental levels

BI Mergler, E Roth, SFA Bruggraber… - Journal of Pharmacy …, 2012 - set-publisher.com
Caco-2 cells may be typically used as a first step to investigate the bioavailability of different
dietary and fortificant forms of iron (Fe) at low levels (< 10 µM) in tissue culture medium …

Comparative bioavailability of synthetic vitamin C and Nutra-C (calcium ascorbate) in Korean healthy volunteers

KM Choi, KM Hoon, HT Won, JD Kim… - Analytical Science …, 2016 - koreascience.kr
The purpose of this study was to compare the relative bioavailability of synthetic Vitamin C
and Nutra-C®(calcium ascorbate) using a randomized parallel pharmacokinetics study …

Vitamin C deficiency in an anticoagulated patient

GM Yousef, LJ Goebel - Journal of general internal medicine, 2013 - Springer
ABSTRACT A 64-year-old woman presented with a hemorrhagic perifollicular rash on her
legs while taking warfarin. After biopsy, vitamin C deficiency was suggested as the …

Biowaiver monograph for ascorbic acid immediate release solid oral dosage forms

HNN Al-Masri - 2016 - repository.najah.edu
Background: Demonstrating similarity in terms of safety and efficacy between innovator
pharmaceutical products and their generic versions is a critical step in granting marketing …