The genetic architecture of quantitative traits

TFC Mackay - Annual review of genetics, 2001 - annualreviews.org
▪ Abstract Phenotypic variation for quantitative traits results from the segregation of alleles at
multiple quantitative trait loci (QTL) with effects that are sensitive to the genetic, sexual, and …

Epistasis: too often neglected in complex trait studies?

Ö Carlborg, CS Haley - Nature Reviews Genetics, 2004 - nature.com
Interactions among loci or between genes and environmental factors make a substantial
contribution to variation in complex traits such as disease susceptibility. Nonetheless, many …

Genetic dissection of phenotypic diversity in farm animals

L Andersson - Nature Reviews Genetics, 2001 - nature.com
Farm animal populations harbour rich collections of mutations with phenotypic effects that
have been purposefully enriched by breeding. Most of these mutations do not have …

The distribution of the effects of genes affecting quantitative traits in livestock

BEN Hayes, ME Goddard - Genetics Selection Evolution, 2001 - Springer
Meta-analysis of information from quantitative trait loci (QTL) mapping experiments was
used to derive distributions of the effects of genes affecting quantitative traits. The two …

Genomewide linkage study in 1,176 affected sister pair families identifies a significant susceptibility locus for endometriosis on chromosome 10q26

SA Treloar, J Wicks, DR Nyholt, GW Montgomery… - The American Journal of …, 2005 - cell.com
Endometriosis is a common gynecological disease that affects up to 10% of women in their
reproductive years. It causes pelvic pain, severe dysmenorrhea, and subfertility. The disease …

[HTML][HTML] Advances in QTL mapping in pigs

MF Rothschild, Z Hu, Z Jiang - International journal of biological …, 2007 - ncbi.nlm.nih.gov
Over the past 15 years advances in the porcine genetic linkage map and discovery of useful
candidate genes have led to valuable gene and trait information being discovered. Early use …

Detection of quantitative trait loci for growth and fatness in pigs

JP Bidanel, D Milan, N Iannuccelli… - Genetics Selection …, 2001 - gse-journal.org
A quantitative trait locus (QTL) analysis of growth and fatness data from a three-generation
experimental cross between Meishan (MS) and Large White (LW) pig breeds is presented …

A molecular genome scan analysis to identify chromosomal regions influencing economic traits in the pig. I. Growth and body composition

M Malek, JCM Dekkers, HK Lee, TJ Baas… - Mammalian …, 2001 - Springer
Genome scans can be employed to identify chromosomal regions and eventually genes
(quantitative trait loci or QTL) that control quantitative traits of economic importance. A three …

QTLs associated with resistance to soybean cyst nematode in soybean: Meta‐analysis of QTL locations

B Guo, DA Sleper, P Lu, JG Shannon… - Crop …, 2006 - Wiley Online Library
Soybean cyst nematode (SCN)(Heterodera glycines Ichinohe) is the most important pest of
soybean [Glycine max (L.) Merr.] in the world. A total of 17 quantitative trait locus (QTL) …

A QTL resource and comparison tool for pigs: PigQTLDB

ZL Hu, S Dracheva, W Jang, D Maglott… - Mammalian …, 2005 - Springer
During the past decade, efforts to map quantitative trait loci (QTL) in pigs have resulted in
hundreds of QTL being reported for growth, meat quality, reproduction, disease resistance …