RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

MicroRNAs (miRNAs) are a class of∼ 22 nucleotide short noncoding RNAs that play key
roles in fundamental cellular processes, including how cells respond to changes in …

A better understanding of human hepatocellular carcinoma (HCC) pathogenesis at the
molecular level will facilitate the discovery of tumor-initiating events. Transcriptome …

RNA editing is a post-transcriptional event that recodes hereditary information. Here we
describe a comprehensive profile of the RNA editome of a male Han Chinese individual …

A fully mature mRNA is usually associated to a reference open reading frame encoding a
single protein. Yet, mature mRNAs contain unconventional alternative open reading frames …

RNA editing enhances the diversity of gene products at the post-transcriptional level.
Approaches for genome-wide identification of RNA editing face two main challenges …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Neurodevelopmental disorders (NDDs) are characterized by aberrant and delayed early-life
development of the brain, leading to deficits in language, cognition, motor behaviour and …

MicroRNAs (miRNAs) are abundant, endogenous, short, noncoding RNAs that act as
important post-transcriptional regulators of gene expression by base-pairing with their target …

Objective Hepatocellular carcinoma (HCC) is a heterogeneous tumour displaying a complex
variety of genetic and epigenetic changes. In human cancers, aberrant post-transcriptional …