Effects of mesenchymal stem cell-derived exosomes on autoimmune diseases

Z Shen, W Huang, J Liu, J Tian, S Wang… - Frontiers in …, 2021 - frontiersin.org
Recent years, the immunosuppressive properties of mesenchymal stem cells (MSCs) have
been demonstrated in preclinical studies and trials of inflammatory and autoimmune …

Pathogenesis of multiple organ injury in COVID-19 and potential therapeutic strategies

M Lopes-Pacheco, PL Silva, FF Cruz… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory disease coronavirus 2 (SARS-CoV-2, formerly 2019-nCoV) is a
novel coronavirus that has rapidly disseminated worldwide, causing the coronavirus disease …

The current status of mesenchymal stromal cells: controversies, unresolved issues and some promising solutions to improve their therapeutic efficacy

D García-Bernal, M García-Arranz… - Frontiers in Cell and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in
advanced therapies with different purposes, most of which are related with inflammatory …

Mesenchymal stem cells for chronic wound healing: current status of preclinical and clinical studies

YZ Huang, M Gou, LC Da, WQ Zhang… - Tissue Engineering Part …, 2020 - liebertpub.com
Healing skin wounds with anatomic and functional integrity, especially under chronic
pathological conditions, remain an enormous challenge. Due to their outstanding …

Biogenesis, composition and potential therapeutic applications of mesenchymal stem cells derived exosomes in various diseases

YG Yuan, JL Wang, YX Zhang, L Li… - International Journal …, 2023 - Taylor & Francis
Exosomes are nanovesicles with a wide range of chemical compositions used in many
different applications. Mesenchymal stem cell-derived exosomes (MSCs-EXOs) are …

Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19

L Tang, Y Jiang, M Zhu, L Chen, X Zhou, C Zhou… - Frontiers of …, 2020 - Springer
Abstract The Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 was identified
in December 2019. The symptoms include fever, cough, dyspnea, early symptom of sputum …

The potential of mesenchymal stem cell therapy for chronic lung disease

FF Cruz, PRM Rocco - Expert Review of Respiratory Medicine, 2020 - Taylor & Francis
Introduction: Mesenchymal stem/stromal cells (MSCs) have been shown to improve lung
function and survival in chronic inflammatory lung diseases, including asthma, chronic …

Current status of clinical trials assessing mesenchymal stem cell therapy for graft versus host disease: a systematic review

Y Li, J Hao, Z Hu, YG Yang, Q Zhou, L Sun… - Stem Cell Research & …, 2022 - Springer
Background Graft-versus-host disease (GVHD) is a common fatal complication of
hematopoietic stem cell transplantation (HSCT), where steroids are used as a treatment …

Analysis of galectin‐3 levels as a source of coronary heart disease risk during periodontitis

G Isola, A Polizzi, A Alibrandi… - Journal of …, 2021 - Wiley Online Library
Abstract Background and Objective Different evidence has shown that Galectins have a key
role as modulators of cell surface functions and signaling in a wide range of inflammatory …

Immune cell dysregulation as a mediator of fibrosis in systemic sclerosis

D Fang, B Chen, A Lescoat, D Khanna… - Nature Reviews …, 2022 - nature.com
Systemic sclerosis (SSc) is a destructive connective tissue disease characterized by
dysregulation of the immune system and fibrosis in the skin and internal organs. The …