1, 2, 3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships

Z Xu, SJ Zhao, Y Liu - European journal of medicinal chemistry, 2019 - Elsevier
Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …

Coumarin-containing hybrids and their anticancer activities

L Zhang, Z Xu - European Journal of Medicinal Chemistry, 2019 - Elsevier
Cancer is the second leading cause of death worldwide, and it results in around 9 million
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …

Latest developments in coumarin-based anticancer agents: mechanism of action and structure–activity relationship studies

M Koley, J Han, VA Soloshonok… - RSC Medicinal …, 2023 - pmc.ncbi.nlm.nih.gov
Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

Traditional application and modern pharmacological research of Artemisia annua L.

X Feng, S Cao, F Qiu, B Zhang - Pharmacology & therapeutics, 2020 - Elsevier
Abstract As a Traditional Chinese Medicine, Artemisia annua L.(A. annua) has been used for
the treatment of various diseases since ancient times, including intermittent fevers due to …

Applications of sesquiterpene lactones: a review of some potential success cases

L Moujir, O Callies, PMC Sousa, F Sharopov… - Applied Sciences, 2020 - mdpi.com
Sesquiterpene lactones, a vast range of terpenoids isolated from Asteraceae species,
exhibit a broad spectrum of biological effects and several of them are already commercially …

A concise review on Artemisia annua L.: A major source of diverse medicinal compounds

R Soni, G Shankar, P Mukhopadhyay… - Industrial Crops and …, 2022 - Elsevier
Malaria is one of the major global health concerns that affect millions of people worldwide
annually, especially people residing in the developing countries. The previously …

Artemisinins as anticancer drugs: Novel therapeutic approaches, molecular mechanisms, and clinical trials

C Xu, H Zhang, L Mu, X Yang - Frontiers in Pharmacology, 2020 - frontiersin.org
Artemisinin and its derivatives have shown broad-spectrum antitumor activities in vitro and in
vivo. Furthermore, outcomes from a limited number of clinical trials provide encouraging …

[HTML][HTML] Nature-derived compounds modulating Wnt/β-catenin pathway: a preventive and therapeutic opportunity in neoplastic diseases

G Sferrazza, M Corti, G Brusotti, P Pierimarchi… - … Pharmaceutica Sinica B, 2020 - Elsevier
The Wnt/β-catenin signaling is a conserved pathway that has a crucial role in embryonic and
adult life. Dysregulation of the Wnt/β-catenin pathway has been associated with diseases …

RETRACTED: Artemisia Extracts and Artemisinin-Based Antimalarials for COVID-19 Management: Could These Be Effective Antivirals for COVID-19 Treatment?

PK Agrawal, C Agrawal, G Blunden - Molecules, 2022 - mdpi.com
As the world desperately searches for ways to treat the coronavirus disease 2019 (COVID-
19) pandemic, a growing number of people are turning to herbal remedies. The Artemisia …

Artemisinin suppresses myocardial ischemia–reperfusion injury via NLRP3 inflammasome mechanism

F Wang, Q Gao, J Yang, C Wang, J Cao, J Sun… - Molecular and Cellular …, 2020 - Springer
Artemisinin is known for its pharmaceutical effect against malaria and received increased
attention for its other potential function. Mounting evidence suggest that artemisinin could …