Intercellular communication is a critical process that ensures cooperation between distinct
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …

Inflammasome is a complex of multiple proteins found in cytoplasm of the cells activated by
infectious and/or non-infectious stimuli. This complex involves caspase-1 activation, leading …

Here, we describe a novel pathogenic entity, the activated PMN (polymorphonuclear
leukocyte, ie, neutrophil)-derived exosome. These CD63+/CD66b+ nanovesicles acquire …

Extracellular vesicles (EV) are small plasma membrane-derived particles released into the
extracellular space by virtually all cell types. Recently, EV have received increased interest …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease characterized by lung
epithelial cell injury, increased (myo) fibroblast activation, and extracellular matrix …

Exosomes are nanosized vesicles released from every cell in the body including those in the
respiratory tract and lungs. They are found in most body fluids and contain a number of …

Premature infants are at high risk for developing bronchopulmonary dysplasia (BPD),
characterized by chronic inflammation and inhibition of lung development, which we have …

Lung injury and inflammation are common characterizes in many pulmonary diseases.
Alveolar epithelial cells, macrophages, pulmonary microvascular endothelial cells, and …

The extracellular matrix (ECM) is a highly dynamic and complex network structure, which
exists in almost all tissues and is the microenvironment that cells rely on for survival. ECM …

Recent research on extracellular vesicles (EVs) has provided new insights into
pathogenesis and potential therapeutic options for acute respiratory distress syndrome …