Persistence alters the interaction between Chlamydia trachomatis and its host cell

MR Brockett, GW Liechti - Infection and Immunity, 2021 - Am Soc Microbiol
In response to stress, the obligate intracellular pathogen Chlamydia trachomatis stops
dividing and halts its biphasic developmental cycle. The infectious, extracellular form of this …

Aberrant Bodies: An Alternative Metabolic Homeostasis Allowing Survivability?

T Kozusnik, SE Adams, G Greub - Microorganisms, 2024 - mdpi.com
The Chlamydiae phylum is comprised of obligate intracellular bacteria including human
pathogens such as Chlamydia trachomatis and lesser-known Chlamydia-related bacteria …

In vitro extracellular replication of Wolbachia endobacteria

LV Behrmann, K Meier, J Vollmer, CC Chiedu… - Frontiers in …, 2024 - frontiersin.org
Obligate intracellular endobacteria of the genus Wolbachia are widespread in arthropods
and several filarial nematodes. Control programs for vector-borne diseases (dengue, Zika …

Spontaneous Aberrant Bodies Formation in Human Pneumocytes Infected with Estrella lausannensis

A Rovero, C Kebbi-Beghdadi, G Greub - Microorganisms, 2023 - mdpi.com
Estrella lausannensis, a Chlamydia-related bacterium isolated from a Spanish river, is
considered as a possible emerging human pathogen. Indeed, it was recently demonstrated …

The Chlamydia-related Waddlia chondrophila encodes functional type II toxin-antitoxin systems

S Ardissone, G Greub - Applied and Environmental Microbiology, 2024 - Am Soc Microbiol
Bacterial toxin-antitoxin (TA) systems are widespread in chromosomes and plasmids of free-
living microorganisms, but only a few have been identified in obligate intracellular species …

Temperature affects the host range of Rhabdochlamydia porcellionis

B Marquis, S Ardissone, G Greub - Applied and Environmental …, 2023 - Am Soc Microbiol
The Rhabdochlamydiaceae family is a recent addition to the Chlamydiae phylum. Its
members were discovered in cockroaches and woodlice, but recent metagenomics surveys …

Genome copy number regulates inclusion expansion, septation, and infectious developmental form conversion in Chlamydia trachomatis

JA Brothwell, M Brockett, A Banerjee… - Journal of …, 2021 - Am Soc Microbiol
ABSTRACT DNA replication is essential for the growth and development of Chlamydia
trachomatis; however, it is unclear how this process contributes to and is controlled by the …

Transcriptional Landscape of Waddlia chondrophila Aberrant Bodies Induced by Iron Starvation

S Ardissone, A Scherler, T Pillonel, V Martin… - Microorganisms, 2020 - mdpi.com
Chronic infections caused by obligate intracellular bacteria belonging to the Chlamydiales
order are related to the formation of persistent developmental forms called aberrant bodies …

[HTML][HTML] Deregulation of the cyclin-dependent kinase inhibitor p27 as a putative candidate for transformation in Chlamydia trachomatis infected mesenchymal stem …

MA Abu-Lubad, W Al-Zereini, MA Al-Zeer - AIMS microbiology, 2023 - ncbi.nlm.nih.gov
Purpose Several pathological conditions might cause the degradation of the cyclin-
dependent kinase inhibitor (CKI) p27 and cell cycle arrest at the G1 phase, including …

[HTML][HTML] Recognition of Chlamydia trachomatis by Toll-Like Receptor 9 is altered during persistence

A Diallo, G Overman, P Sah, GW Liechti - bioRxiv, 2024 - ncbi.nlm.nih.gov
Abstract Toll-like receptor 9 (TLR9) is an innate immune receptor that localizes to
endosomes in antigen presenting cells and recognizes single stranded unmethylated CpG …