Macrophage M1/M2 polarization

C Yunna, H Mengru, W Lei, C Weidong - European journal of …, 2020 - Elsevier
Macrophages can be affected by a variety of factors to change their phenotype and thus
affect their function. Activated macrophages are usually divided into two categories, M1-like …

Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics

A Carnicer-Lombarte, ST Chen… - … in Bioengineering and …, 2021 - frontiersin.org
The implantation of any foreign material into the body leads to the development of an
inflammatory and fibrotic process—the foreign body reaction (FBR). Upon implantation into a …

A natural biological adhesive from snail mucus for wound repair

T Deng, D Gao, X Song, Z Zhou, L Zhou, M Tao… - Nature …, 2023 - nature.com
The discovery of natural adhesion phenomena and mechanisms has advanced the
development of a new generation of tissue adhesives in recent decades. In this study, we …

Regulation of macrophage polarization through surface topography design to facilitate implant-to-bone osteointegration

Y Zhu, H Liang, X Liu, J Wu, C Yang, TM Wong… - Science …, 2021 - science.org
Proper immune responses are critical for successful biomaterial implantation. Here, four
scales of honeycomb-like TiO2 structures were custom made on titanium (Ti) substrates to …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

The multifaceted roles of macrophages in bone regeneration: a story of polarization, activation and time

C Schlundt, H Fischer, CH Bucher, C Rendenbach… - Acta biomaterialia, 2021 - Elsevier
To present knowledge, macrophages are found in all tissues of the human body. They are a
cell population with high plasticity which come with a multitude of functions which appear to …

A 3D-printed PRP-GelMA hydrogel promotes osteochondral regeneration through M2 macrophage polarization in a rabbit model

G Jiang, S Li, K Yu, B He, J Hong, T Xu, J Meng, C Ye… - Acta biomaterialia, 2021 - Elsevier
Osteochondral regeneration is an orchestrated process of inflammatory immunity, host cell
response, and implant degradation in tissue engineering. Here, the effects of a platelet-rich …

Extracellular‐matrix‐reinforced bioinks for 3D bioprinting human tissue

MM De Santis, HN Alsafadi, S Tas… - Advanced …, 2021 - Wiley Online Library
Recent advances in 3D bioprinting allow for generating intricate structures with dimensions
relevant for human tissue, but suitable bioinks for producing translationally relevant tissue …

Biomaterials: foreign bodies or tuners for the immune response?

E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

Extracellular matrix-based materials for regenerative medicine

GS Hussey, JL Dziki, SF Badylak - Nature Reviews Materials, 2018 - nature.com
In tissue engineering and regenerative medicine, a biomaterial provides mechanical support
and biochemical signals to encourage cell attachment and modulate cell behaviour …