ERBB3, a member of the epidermal growth factor receptor (EGFR) family, is unique in that its
tyrosine kinase domain is functionally defective. It is activated by neuregulins, by other …

Oral squamous cell carcinoma (OSCC) is a common cancer characterised by low survival
rate and poor prognosis. The multistep process of oral carcinogenesis is affected by multiple …

Purpose The human epidermal growth factor receptor (HER) family consists of four
members: ErbB-1 (HER1), ErbB-2 (HER2), ErbB-3 (HER3), and ErbB-4 (HER4). These …

Background HER3 (erbB-3) is a member of the epidermal growth factor receptor (EGFR)
family. After dimerization with other members of the EGFR family several signal transduction …

Background: The role of human epidermal growth factor receptor (HER) 3 and HER4 has
been elucidated in gastric cancer. HER1 and HER2 overexpression are regarded as …

Importance of the field: Head and neck squamous cell carcinoma (HNSCC) is the eighth
leading cause of cancer death worldwide. Despite advances in surgery and chemoradiation …

Epidermal growth factor receptor (EGFR) is highly expressed in head and neck squamous
cell carcinoma (HNSCC) and correlates with poor prognosis. EGFR has been demonstrated …

Epidermal growth factor receptor (EGFR), a member of the ErbB family of receptor tyrosine
kinases (RTKs), is highly expressed in head and neck squamous cell carcinoma (HNSCC) …

Increased expression of the epidermal growth factor (EGF) receptors, HER1 and HER2 are
related to poor prognosis in most cancers studied. Recently, a high expression of the two …

The aim of this systematic review and meta-analysis was to evaluate the current evidence in
relation to the clinicopathological and prognostic significance of epidermal growth factor …