Axon initial segment (AIS) is the most excitable subcellular domain of a neuron for action
potential initiation. AISs of cortical projection neurons (PNs) receive GABAergic synaptic …

Homeostatic plasticity maintains the stability of functional brain networks. The axon initial
segment (AIS), where action potentials start, undergoes dynamic adjustment to exert …

Imbalance between excitation and inhibition in the cerebral cortex is one of the main
theories in neuropsychiatric disorder pathophysiology. Cortical inhibition is finely regulated …

Detailed characterization of interneuron subtypes in primary visual cortex (V1) has greatly
contributed to understanding visual perception, yet the role of chandelier cells (ChCs) in …

Detailed characterization of interneuron types in primary visual cortex (V1) has greatly
contributed to understanding visual perception, yet the role of chandelier cells (ChCs) in …

The generation of motor behaviors and the performance of complex cognitive tasks rely on
sequential activity in specific brain structures. The mechanisms of learning and retrieval of …

Our visual perception is not simply a continuous picture of the world. It is heavily influenced
by context, prior experience and most importantly: predictions. We constantly predict the …

O córtex pré-frontal (CPF) é a região do cérebro responsável por funções cognitivas e
executivas especializadas. Por sua vez, o CPF medial é a sub-região que desempenha um …

The advances in in vivo dual-photon fluorescence microscopy157, 158 and the
development of genetically encoded fluorescent biosensors148, 159 have revolutionized …