Avian-to-human receptor-binding adaptation by influenza A virus hemagglutinin H4

H Song, J Qi, H Xiao, Y Bi, W Zhang, Y Xu, F Wang… - Cell reports, 2017 - cell.com
Low-pathogenicity avian influenza viruses (LPAIVs) have caused a global concern to public
health since the first novel LPAIV H7N9 outbreak occurred. The receptor-binding properties …

[HTML][HTML] The H4 subtype of avian influenza virus: a review of its historical evolution, global distribution, adaptive mutations and receptor binding properties

J Liu, Z Liang, W Sun, W Hua, S Huang, F Wen - Poultry Science, 2024 - Elsevier
The H4 subtype of avian influenza virus (AIV) exhibits a wide host range and is commonly
found in migratory waterfowl. Recent studies have revealed that the H4N6 AIV can infect …

Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006–2016

SA Bergervoet, SBE Pritz-Verschuren, JL Gonzales… - Scientific reports, 2019 - nature.com
In this study, we explore the circulation of low pathogenic avian influenza (LPAI) viruses in
wild birds and poultry in the Netherlands. Surveillance data collected between 2006 and …

Survey of low pathogenic avian influenza viruses in live poultry markets in Guangxi Province, Southern China, 2016–2019

S Luo, Z Xie, M Li, D Li, L Xie, J Huang, M Zhang… - Scientific Reports, 2021 - nature.com
Low pathogenic avian influenza viruses (LPAIVs) have been widespread in poultry and wild
birds throughout the world for many decades. LPAIV infections are usually asymptomatic or …

Genetic and Biological Characteristics of Duck-Origin H4N6 Avian Influenza Virus Isolated in China in 2022

T Li, C Zhao, Y Guo, J Dong, F Du, Y Zhou, S Shu… - Viruses, 2024 - mdpi.com
The interaction between migratory birds and domestic waterfowl facilitates viral co-
infections, leading to viral reassortment and the emergence of novel viruses. In 2022 …

Cross-reactive antibodies binding to H4 hemagglutinin protect against a lethal H4N6 influenza virus challenge in the mouse model

F Amanat, P Meade, S Strohmeier… - Emerging microbes & …, 2019 - Taylor & Francis
Influenza viruses of the H4 subtype are widespread in wild birds, circulate in domestic
poultry, readily infect mammals, and tolerate the insertion of a polybasic cleavage site. In …

Surveillance of live poultry markets for low pathogenic avian influenza viruses in Guangxi Province, Southern China, from 2012–2015

S Luo, Z Xie, Z Xie, L Xie, L Huang, J Huang, X Deng… - Scientific reports, 2017 - nature.com
Infections with low pathogenic avian influenza viruses (LPAIVs) can be mild or asymptomatic
in poultry; however, in humans, LPAIVs can cause severe infections and death, as …

Epidemiology and Biological Characteristics of Influenza A (H4N6) Viruses from Wild Birds

X Song, J Tian, M Li, X Bai, Z Zhao, J Shi… - Emerging Microbes & …, 2024 - Taylor & Francis
During the active surveillance, we isolated nine H4N6 subtype influenza A viruses from wild
birds in China. To reveal the epidemiology and biology characteristics of H4 subtype …

Differences in highly pathogenic H5N6 avian influenza viral pathogenicity and inflammatory response in chickens and ducks

B Wang, Q Su, J Luo, M Li, Q Wu, H Chang… - Frontiers in …, 2021 - frontiersin.org
Infection with H5N6 highly pathogenic avian influenza virus caused high mortality in
chickens, while ducks often appear to be asymptomatic. But, some recent H5Nx subtype …

Susceptibility of chickens to low pathogenic avian influenza (LPAI) Viruses of wild bird–and poultry–associated subtypes

SA Bergervoet, EA Germeraad, M Alders, MM Roose… - Viruses, 2019 - mdpi.com
Analysis of low pathogenic avian influenza (LPAI) viruses circulating in the Netherlands in a
previous study revealed associations of specific hemagglutinin (HA) and neuraminidase …