Native mass spectrometry (MS) involves the analysis and characterization of
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …

Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

Carbohydrates possess a variety of distinct features with stereochemistry playing a
particularly important role in distinguishing their structure and function. Monosaccharide …

Simple Summary The detection of colorectal cancer (CRC) at an early stage is increasing
due to the implementation of screening programs. Local excision of early CRC is potentially …

Galectins (formerly known as “S-type lectins”) are a subfamily of soluble proteins that
typically bind β-galactoside carbohydrates with high specificity. They are present in many …

N‐glycome analysis in total plasma or serum yields information about the levels and
glycosylation patterns of major plasma glycoproteins, including immunoglobulins, acute …

Glycosylation changes are key molecular events in tumorigenesis, progression and
glycosyltransferases play a vital role in the this process. FUT8 belongs to the …

The choice for adjuvant chemotherapy in stage II colorectal cancer is controversial as many
patients are cured by surgery alone and it is difficult to identify patients with high risk of …

Glycans are fundamental cellular building blocks, involved in many organismal functions.
Advances in glycomics are elucidating the essential roles of glycans. Still, it remains …