miRNA: a promising therapeutic target in cancer

A Menon, N Abd-Aziz, K Khalid, CL Poh… - International journal of …, 2022 - mdpi.com
microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by
complementarity pairing. Since discovery, they have been reported to be involved in a …

MicroRNA replacement therapy in cancer

H Mollaei, R Safaralizadeh… - Journal of cellular …, 2019 - Wiley Online Library
Despite the recent progress in cancer management approaches, the mortality rate of cancer
is still growing and there are lots of challenges in the clinics in terms of novel therapeutics …

Progress in microRNA delivery

Y Zhang, Z Wang, RA Gemeinhart - Journal of controlled release, 2013 - Elsevier
MicroRNAs (miRNAs) are non-coding endogenous RNAs that direct post-transcriptional
regulation of gene expression by several mechanisms. Activity is primarily through binding …

Targeting noncoding RNAs in disease

BD Adams, C Parsons, L Walker… - The Journal of …, 2017 - Am Soc Clin Investig
Many RNA species have been identified as important players in the development of chronic
diseases, including cancer. Over the past decade, numerous studies have highlighted how …

microRNA‐based diagnostic and therapeutic applications in cancer medicine

LF Sempere, AS Azmi, A Moore - Wiley Interdisciplinary …, 2021 - Wiley Online Library
It has been almost two decades since the first link between microRNAs and cancer was
established. In the ensuing years, this abundant class of short noncoding regulatory RNAs …

Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors

H Wang, Y Jiang, H Peng, Y Chen, P Zhu… - Advanced drug delivery …, 2015 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Because
of significant changes in their expression in cancer, miRNAs are believed to be key factors in …

[HTML][HTML] The fundamental role of miR-10b in metastatic cancer

P Sheedy, Z Medarova - American journal of cancer research, 2018 - ncbi.nlm.nih.gov
Small, non-coding strands of RNA have been identified as a significant player in the
pathology of cancer. One of the first miRNAs to be shown as having aberrant expression in …

MicroRNAs‐based imaging techniques in cancer diagnosis and therapy

M Keshavarzi, S Sorayayi… - Journal of cellular …, 2017 - Wiley Online Library
Cancer is one of the most serious global health concerns in different populations. Several
studies indicated that there are many potentially promising cellular and molecular targets for …

Nano-chemotherapeutics: maximising lymphatic drug exposure to improve the treatment of lymph-metastatic cancers

GM Ryan, LM Kaminskas, CJH Porter - Journal of Controlled Release, 2014 - Elsevier
Nano-sized drug delivery systems incorporating chemotherapeutic drugs (“nano-
chemotherapeutics”) have been widely employed for the treatment of solid tumours. The …

Highly sensitive detection of multiple microRNAs by high-performance liquid chromatography coupled with long and short probe-based recycling amplification

T Qi, C Song, J He, W Shen, D Kong, H Shi… - Analytical …, 2020 - ACS Publications
This report demonstrated the utility of high-performance liquid chromatography (HPLC)-
fluorescence detection for selective separation and sensitive quantification of multiple …