Novel treatment strategies for chronic kidney disease: insights from the animal kingdom

P Stenvinkel, J Painer, M Kuro-o, M Lanaspa… - Nature Reviews …, 2018 - nature.com
Many of the> 2 million animal species that inhabit Earth have developed survival
mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration …

Soluble biglycan as a biomarker of inflammatory renal diseases

LTH Hsieh, MV Nastase, J Zeng-Brouwers… - The international journal …, 2014 - Elsevier
Chronic renal inflammation is often associated with a progressive accumulation of various
extracellular matrix constituents, including several members of the small leucine-rich …

[图书][B] The biology and conservation of wild felids

DW Macdonald, AJ Loveridge - 2010 - books.google.com
The editors utilize their 50 years of combined experience in professional engagement with
the behaviour and ecology of wild felids to draw together a unique network of the world's …

Purging of deleterious burden in the endangered Iberian lynx

D Kleinman-Ruiz, M Lucena-Perez… - Proceedings of the …, 2022 - National Acad Sciences
Deleterious mutations continuously accumulate in populations, building up a burden that
can threaten their survival, particularly in small populations when inbreeding exposes …

Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx

F Abascal, A Corvelo, F Cruz, JL Villanueva-Cañas… - Genome biology, 2016 - Springer
Background Genomic studies of endangered species provide insights into their evolution
and demographic history, reveal patterns of genomic erosion that might limit their viability …

Extended and continuous decline in effective population size results in low genomic diversity in the world's rarest hyena species, the brown hyena

MV Westbury, S Hartmann, A Barlow… - Molecular biology …, 2018 - academic.oup.com
Hyenas (family Hyaenidae), as the sister group to cats (family Felidae), represent a deeply
diverging branch within the cat-like carnivores (Feliformia). With an estimated population …

Feline Leukemia Virus and Other Pathogens as Important Threats to the Survival of the Critically Endangered Iberian Lynx (Lynx pardinus)

ML Meli, V Cattori, F Martínez, G López, A Vargas… - PLoS …, 2009 - journals.plos.org
Background The Iberian lynx (Lynx pardinus) is considered the most endangered felid
species in the world. In order to save this species, the Spanish authorities implemented a …

Novel efficient genome-wide SNP panels for the conservation of the highly endangered Iberian lynx

D Kleinman-Ruiz, B Martínez-Cruz, L Soriano… - BMC genomics, 2017 - Springer
Abstract Background The Iberian lynx (Lynx pardinus) has been acknowledged as the most
endangered felid species in the world. An intense contraction and fragmentation during the …

Possible extinction vortex for a population of Iberian lynx on the verge of extirpation

F Palomares, JA Godoy, JV LÓPEZ‐BAO… - Conservation …, 2012 - Wiley Online Library
Theory suggests that demographic and genetic traits deteriorate (ie, fitness and genetic
diversity decrease) when populations become small, and that such deterioration could …

Genetics at the verge of extinction: insights from the I berian lynx

M Casas‐Marce, L Soriano, JV López‐Bao… - Molecular …, 2013 - Wiley Online Library
Population viability might become compromised by the loss of genetic diversity and the
accumulation of inbreeding resulting from population decline and fragmentation. The I …