Functionalizing DNA origami to investigate and interact with biological systems

GA Knappe, EC Wamhoff, M Bathe - Nature Reviews Materials, 2023 - nature.com
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

DNA origami: scaffolds for creating higher order structures

F Hong, F Zhang, Y Liu, H Yan - Chemical reviews, 2017 - ACS Publications
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

Chemistries for DNA nanotechnology

M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

Challenges and perspectives of DNA nanostructures in biomedicine

A Keller, V Linko - Angewandte Chemie International Edition, 2020 - Wiley Online Library
DNA nanotechnology holds substantial promise for future biomedical engineering and the
development of novel therapies and diagnostic assays. The subnanometer‐level …

On the stability of DNA origami nanostructures in low‐magnesium buffers

C Kielar, Y Xin, B Shen, MA Kostiainen… - Angewandte …, 2018 - Wiley Online Library
DNA origami structures have great potential as functional platforms in various biomedical
applications. Many applications, however, are incompatible with the high Mg2+ …

Programmable and multifunctional DNA‐based materials for biomedical applications

Y Zhang, J Tu, D Wang, H Zhu, SK Maity… - Advanced …, 2018 - Wiley Online Library
DNA encodes the genetic information; recently, it has also become a key player in material
science. Given the specific Watson–Crick base‐pairing interactions between only four types …

Evolution of structural DNA nanotechnology

S Nummelin, J Kommeri, MA Kostiainen… - Advanced …, 2018 - Wiley Online Library
The research field entitled structural DNA nanotechnology emerged in the beginning of the
1980s as the first immobile synthetic nucleic acid junctions were postulated and …

Protein coating of DNA nanostructures for enhanced stability and immunocompatibility

H Auvinen, H Zhang, Nonappa… - Advanced …, 2017 - Wiley Online Library
Fully addressable DNA nanostructures, especially DNA origami, possess huge potential to
serve as inherently biocompatible and versatile molecular platforms. However, their use as …

DNA origami-based protein networks: from basic construction to emerging applications

G Kong, M Xiong, L Liu, L Hu, HM Meng, G Ke… - Chemical Society …, 2021 - pubs.rsc.org
Natural living systems are driven by delicate protein networks whose functions are precisely
controlled by many parameters, such as number, distance, orientation, and position …

DNA origami protection and molecular interfacing through engineered sequence-defined peptoids

ST Wang, MA Gray, S Xuan, Y Lin… - Proceedings of the …, 2020 - National Acad Sciences
DNA nanotechnology has established approaches for designing programmable and
precisely controlled nanoscale architectures through specific Watson− Crick base-pairing …