[HTML][HTML] An overview on the potential of natural products as ureases inhibitors: A review

LV Modolo, AX de Souza, LP Horta, DP Araujo… - Journal of Advanced …, 2015 - Elsevier
Ureases, enzymes that catalyze urea hydrolysis, have received considerable attention for
their impact on living organisms' health and life quality. On the one hand, the persistence of …

Biosynthesis and molecular actions of specialized 1, 4-naphthoquinone natural products produced by horticultural plants

JR Widhalm, D Rhodes - Horticulture Research, 2016 - academic.oup.com
Abstract The 1, 4-naphthoquinones (1, 4-NQs) are a diverse group of natural products found
in every kingdom of life. Plants, including many horticultural species, collectively synthesize …

Enhancing selective photooxidation through Co–Nx-doped carbon materials as singlet oxygen photosensitizers

W Wu, Q Zhang, X Wang, C Han, X Shao, Y Wang… - ACS …, 2017 - ACS Publications
Singlet oxygen (1O2) is considered one of the most effective and selective oxygen agents.
However, it is always obtained with the help of heavy atoms in the photosensitizers to …

Agricultural uses of juglone: Opportunities and challenges

AKMM Islam, JR Widhalm - Agronomy, 2020 - mdpi.com
Application of conventional synthetic pesticides and agrochemicals has boosted the yield
and productivity of crops by reducing pest infestation and promoting crop growth yet …

Convergent evolution of plant specialized 1, 4-naphthoquinones: metabolism, trafficking, and resistance to their allelopathic effects

GW Meyer, MA Bahamon Naranjo… - Journal of …, 2021 - academic.oup.com
Abstract Plant 1, 4-naphthoquinones encompass a class of specialized metabolites known
to mediate numerous plant–biotic interactions. This class of compounds also presents a …

Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities

MY Mentese, H Bayrak, Y Uygun, A Mermer… - European Journal of …, 2013 - Elsevier
Abstract Norfloxacin was converted to 7-(4-amino-2-fluorophenyl) piperazin derivative (2)
via the formation of nitro compound. The synthesis of the norfloxacin derivatives containing …

Green tea polyphenol epigallocatechin-3-gallate (EGCG) induced intermolecular cross-linking of membrane proteins

R Chen, JB Wang, XQ Zhang, J Ren… - Archives of Biochemistry …, 2011 - Elsevier
Increasing evidence has demonstrated that EGCG possesses prooxidant potential in
biological systems, including modifying proteins, breaking DNA strands and inducing the …

Probing sulphamethazine and sulphamethoxazole based Schiff bases as urease inhibitors; synthesis, characterization, molecular docking and ADME evaluation

A Hamad, MA Khan, I Ahmad, A Imran, R Khalil… - Bioorganic …, 2020 - Elsevier
In the current study, a novel series of Schiff base derivatives of (E)-4-(benzylideneamino)-N-
(4, 6-dimethylpyrimidin-2-yl) benzenesulfonamide (3a-3f) and (E)-4-(benzylideneamino)-N …

Plant‐derived urease inhibitors as alternative chemotherapeutic agents

STS Hassan, M Žemlička - Archiv Der Pharmazie, 2016 - Wiley Online Library
Inhibition of the metalloenzyme urease has important pharmacologic applications in the field
of antiulcer and antigastric cancer agents. Urease is involved in many serious infections …

Antimicrobial and antiurease activities of newly synthesized morpholine derivatives containing an azole nucleus

H Bektaş, Ş Ceylan, N Demirbaş… - Medicinal Chemistry …, 2013 - Springer
Abstract 2-[6-(Morpholin-4-yl) pyridin-3-ylamino] acetohydrazide (4) was obtained starting
from 6-morpholin-4-ylpyridin-3-amine (2) via the formation of ester (3) and then converted to …