Pathophysiology of delayed cerebral ischemia after subarachnoid hemorrhage: a review

WS Dodd, D Laurent, AS Dumont… - Journal of the …, 2021 - Am Heart Assoc
Delayed cerebral ischemia is a major predictor of poor outcomes in patients who suffer
subarachnoid hemorrhage. Treatment options are limited and often ineffective despite many …

Delayed cerebral ischemia after subarachnoid hemorrhage

A Ikram, MA Javaid, S Ortega-Gutierrez, M Selim… - Journal of Stroke and …, 2021 - Elsevier
Delayed cerebral ischemia (DCI) is the most feared complication of aneurysmal
subarachnoid hemorrhage (aSAH). It increases the mortality and morbidity associated with …

Antiplatelet management for stent-assisted coiling and flow diversion of ruptured intracranial aneurysms: a DELPHI consensus statement

JM Ospel, P Brouwer, F Dorn, A Arthur… - American Journal …, 2020 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: There is a paucity of data regarding antiplatelet
management strategies in the setting of stent-assisted coiling/flow diversion for ruptured …

Trends in dual antiplatelet therapy use for neurointerventional procedures for the management of intracranial aneurysms

BM Meyer, JK Campos, JC Collard de Beaufort, I Chen… - Biomedicines, 2023 - mdpi.com
The use of periprocedural dual antiplatelet therapy (DAPT) has significantly evolved along
with innovations in the endovascular management of intracranial aneurysms. Historically …

Ginsenoside Rh4 inhibits breast cancer growth through targeting histone deacetylase 2 to regulate immune microenvironment and apoptosis

F Dong, L Qu, Z Duan, Y He, X Ma, D Fan - Bioorganic Chemistry, 2023 - Elsevier
High expression of histone deacetylase 2 (HDAC2) is recognized as a marker of invasive
breast cancer (BC). HDAC2 is not only responsible for enhancing tumor cell growth …

An updated review on glycoprotein IIb/IIIa inhibitors as antiplatelet agents: basic and clinical perspectives

J Sharifi-Rad, F Sharopov, SM Ezzat, W Zam… - High Blood Pressure & …, 2023 - Springer
Abstract The glycoprotein (GP) IIb/IIIa receptor is found integrin present in platelet
aggregations. GP IIb/IIIa antagonists interfere with platelet cross-linking and platelet-derived …

Role of platelets in the pathogenesis of delayed injury after subarachnoid hemorrhage

A Dienel, P Kumar T, SL Blackburn… - Journal of Cerebral …, 2021 - journals.sagepub.com
Aneurysmal subarachnoid hemorrhage (aSAH) patients develop delayed cerebral ischemia
and delayed deficits (DCI) within 2 weeks of aneurysm rupture at a rate of approximately …

Endovascular therapy versus microsurgical clipping of unruptured wide-neck aneurysms: a prospective multicenter study with propensity score analysis

JR Mascitelli, J Mocco, T Hardigan, BK Hendricks… - Journal of …, 2021 - thejns.org
OBJECTIVE Numerous techniques have been developed to treat wide-neck aneurysms
(WNAs), each with different safety and efficacy profiles. Few studies have compared …

The use of cangrelor in neurovascular interventions: a multicenter experience

GM Cortez, A Monteiro, N Sourour, F Clarençon… - Neuroradiology, 2021 - Springer
Purpose Thromboembolic events represent the most common procedure-related
complication associated with neurointerventions. Cangrelor is a potent, intravenous (IV) …

Use of Tirofiban to Prevent Ischemic Events in Patients with CYP2C19 Loss-of-Function Alleles during Flow Diversion of Intracranial Aneurysm: A Multicenter Cohort …

Y Zhou, H Kang, W Li, B Luo, C Wang, R Xie… - Translational stroke …, 2024 - Springer
To analyze the effect of tirofiban on ischemic events in CYP2C19 loss-of-function (LOF)
allele carriers during pipeline embolization device (PED) implantation. Demographic …