Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

Melatonin is an old and ubiquitous molecule in nature showing multiple mechanisms of
action and functions in practically every living organism. In mammals, pineal melatonin …

Targeting mitochondrial quality control with melatonin has been found promising for
attenuating diabetic cardiomyopathy (DCM), although the underlying mechanisms remain …

Excess weight and obesity are severe public health threats worldwide. Recent evidence
demonstrates that gut microbiota dysbiosis contributes to obesity and its comorbidities. The …

Modern lifestyle has profoundly modified human sleep habits. Sleep duration has shortened
over recent decades from 8 to 6.5 hours resulting in chronic sleep deprivation. Additionally …

Obesity is the result of energy intake chronically exceeding energy expenditure. Classical
treatments against obesity do not provide a satisfactory long‐term outcome for the majority of …

Introduction Melatonin has been studied in headache disorders. Amitriptyline is efficacious
for migraine prevention, but its unfavourable side effect profile limits its use. Methods A …

Background & aims Melatonin may benefit diabetic people with coronary heart disease
(CHD) through its beneficial effects on biomarkers of oxidative stress and cardio-metabolic …

Melatonin, as a neuroendocrine hormone, is produced primarily by the pineal gland.
Melatonin, a pleotropic molecule, acts as a free radical scavenger, antioxidant, and regulator …

Diabetic brains are more vulnerable to ischemia‐reperfusion injury. Previous studies have
proved that melatonin could protect against cerebral ischemia‐reperfusion (CIR) injury in …