Although death is inevitable, individuals have long sought to alter the course of the ageing process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …
JM Guirguis-Blake, CV Evans, LA Perdue, SI Bean… - Jama, 2022 - jamanetwork.com
Importance Low-dose aspirin is used for primary cardiovascular disease prevention and may have benefits for colorectal cancer prevention. Objective To review the benefits and …
2019 American Geriatrics Society Beers … - Journal of the …, 2019 - Wiley Online Library
The American Geriatrics Society (AGS) Beers Criteria®(AGS Beers Criteria®) for Potentially Inappropriate Medication (PIM) Use in Older Adults are widely used by clinicians, educators …
J Burn, H Sheth, F Elliott, L Reed, F Macrae, JP Mecklin… - The Lancet, 2020 - thelancet.com
Background Lynch syndrome is associated with an increased risk of colorectal cancer and with a broader spectrum of cancers, especially endometrial cancer. In 2011, our group …
Background Aspirin is a well-established therapy for the secondary prevention of cardiovascular events. However, its role in the primary prevention of cardiovascular disease …
Background In the primary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE) trial, now published in the Journal, we report that the daily use of aspirin did not …
Y Ge, M Zhou, C Chen, X Wu, X Wang - Biochimie, 2022 - Elsevier
AMPK is an important kinase regulating energy homeostasis and also a key protein involved in a variety of signal transduction pathways. It plays a vitally regulatory role in cellular …
L Liu, W Chen, H Zhou, W Duan, S Li, X Huo… - Stroke and vascular …, 2020 - svn.bmj.com
Aim Stroke is the leading cause of disability and death in China. Ischaemic stroke accounts for about 60%–80% of all strokes. It is of considerable significance to carry out …
HE Bays, PR Taub, E Epstein, ED Michos… - American journal of …, 2021 - Elsevier
Given rapid advancements in medical science, it is often challenging for the busy clinician to remain up-to-date on the fundamental and multifaceted aspects of preventive cardiology and …