Emerging roles and functional mechanisms of PIWI-interacting RNAs
X Wang, A Ramat, M Simonelig, MF Liu - Nature Reviews Molecular …, 2023 - nature.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that associate with
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …
Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs
C Wang, H Lin - Genome Biology, 2021 - Springer
PIWI proteins, a subfamily of PAZ/PIWI Domain family RNA-binding proteins, are best known
for their function in silencing transposons and germline development by partnering with …
for their function in silencing transposons and germline development by partnering with …
Functions of PIWI proteins in gene regulation: new arrows added to the piRNA quiver
A Ramat, M Simonelig - Trends in Genetics, 2021 - cell.com
Piwi-interacting RNAs (piRNAs) and PIWI proteins play key functions in a wide range of
biological and developmental processes through the regulation of cellular mRNAs, in …
biological and developmental processes through the regulation of cellular mRNAs, in …
[HTML][HTML] A heterochromatin-specific RNA export pathway facilitates piRNA production
MF ElMaghraby, PR Andersen, F Pühringer… - Cell, 2019 - cell.com
PIWI-interacting RNAs (piRNAs) guide transposon silencing in animals. The 22–30 nt
piRNAs are processed in the cytoplasm from long non-coding RNAs that often lack RNA …
piRNAs are processed in the cytoplasm from long non-coding RNAs that often lack RNA …
The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation
Abstract The PIWI-interacting RNA (piRNA) pathway protects genome integrity in part
through establishing repressive heterochromatin at transposon loci. Silencing requires …
through establishing repressive heterochromatin at transposon loci. Silencing requires …
The piRNA pathway in Drosophila ovarian germ and somatic cells
K Sato, MC Siomi - Proceedings of the Japan Academy, Series B, 2020 - jstage.jst.go.jp
RNA silencing refers to gene silencing pathways mediated by small non-coding RNAs,
including microRNAs. Piwi-interacting RNAs (piRNAs) constitute the largest class of small …
including microRNAs. Piwi-interacting RNAs (piRNAs) constitute the largest class of small …
The birth of piRNAs: how mammalian piRNAs are produced, originated, and evolved
Abstract PIWI-interacting RNAs (piRNAs), small noncoding RNAs 24–35 nucleotides long,
are essential for animal fertility. They play critical roles in a range of functions, including …
are essential for animal fertility. They play critical roles in a range of functions, including …
Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery
Nuclear Argonaute proteins, guided by small RNAs, mediate sequence-specific
heterochromatin formation. The molecular principles that link Argonaute-small RNA …
heterochromatin formation. The molecular principles that link Argonaute-small RNA …
piRNA‐ and siRNA‐mediated transcriptional repression in Drosophila, mice, and yeast: new insights and biodiversity
R Onishi, S Yamanaka, MC Siomi - EMBO reports, 2021 - embopress.org
Abstract The PIWI‐interacting RNA (piRNA) pathway acts as a self‐defense mechanism
against transposons to maintain germline genome integrity. Failures in the piRNA pathway …
against transposons to maintain germline genome integrity. Failures in the piRNA pathway …
Su (var) 2-10 and the SUMO pathway link piRNA-guided target recognition to chromatin silencing
Regulation of transcription is the main mechanism responsible for precise control of gene
expression. Whereas the majority of transcriptional regulation is mediated by DNA-binding …
expression. Whereas the majority of transcriptional regulation is mediated by DNA-binding …