[HTML][HTML] Stem cells in kidney ischemia: from inflammation and fibrosis to renal tissue regeneration

R Cianci, M Simeoni, E Cianci, O De Marco… - International Journal of …, 2023 - mdpi.com
Ischemic nephropathy consists of progressive renal function loss due to renal hypoxia,
inflammation, microvascular rarefaction, and fibrosis. We provide a literature review focused …

Dual opposed survival-supporting and death-promoting roles of autophagy in cancer cells: a concise review

ES El-Shafey, ES Elsherbiny - Current Chemical Biology, 2020 - ingentaconnect.com
Autophagy is a well-maintained process by which the cells recycle intracellular materials to
maintain homeostasis in various cellular functions. However, autophagy is a defensive …

Mesenchymal stem cells: a promising therapeutic tool for acute kidney injury

RE Selim, HH Ahmed, SH Abd-Allah, GM Sabry… - Applied biochemistry …, 2019 - Springer
Acute kidney injury (AKI) is a rapid loss of renal function. It has high mortality rates. Still,
renal replacement therapy is considered the best solution for recovering AKI. This opens a …

Ziziphus spina‐christi (L.) fortified with Camellia sinensis mediates apoptosis, Notch‐1 signaling, and mitigates obesity‐induced non‐alcoholic fatty liver

GM El Seedy, ES El‐Shafey… - Journal of Food …, 2021 - Wiley Online Library
The habit of drinking tea is highly prevalent and could be utilized to introduce more health
benefits through fortification with medicinal plants. The purpose of this analysis was to …

The role of apoptosis and autophagy in the insulin-enhancing activity of oxovanadium (IV) bipyridine complex in streptozotocin-induced diabetic mice

ES El-Shafey, ES Elsherbiny - Biometals, 2020 - Springer
Metal-based therapies (eg Vanadium) possess an attractive proposition in medicinal
treatment of diabetes mellitus. Defective insulin secretion can result from impaired β-cell …

Possible selective cytotoxicity of vanadium complex on breast cancer cells involving pathophysiological pathways

ES El-Shafey, ES Elsherbiny - Anti-Cancer Agents in Medicinal …, 2019 - ingentaconnect.com
Background: Triple-Negative Breast Cancers (TNBC) are among the most aggressive and
therapyresistant breast tumors. Development of new treatment strategies that target …

Fortification of biscuit with sidr leaf and flaxseed mitigates immunosuppression and nephrotoxicity induced by cyclosporine A

GM El Seedy, ES El‐Shafey… - Journal of Food …, 2021 - Wiley Online Library
The focus of consumers in healthy food turned to the possible health benefits of particular
foods and food ingredients. This study aimed to evaluate the newly fortified biscuits …

Therapeutic potential of a 2, 2'-bipyridine-based vanadium (IV) complex on HepG2 cells: cytotoxic effects and molecular targeting

ES El-Shafey, ES Elsherbiny - Egyptian Journal of Basic and …, 2023 - Taylor & Francis
Vanadium complexes as non-platinum metallic drugs have gained considerable importance
as an appropriate candidate for cancer treatment The study aimed to investigate the patent …

Possible renal repairing mechanisms of mesenchymal stem cells in cyclosporine-mediated nephrotoxicity: endothelial viability and hemodynamics

EAM Toson, HH Ahmed, HAM El-mezayen… - The Indonesian …, 2019 - inabj.org
BACKGROUND: Stem cell-based therapy may represent the first realistic option for tissue
repairing and regeneration. Mesenchymal stem cells (MSCs) are proved to be involved in …

Impact of proinflammatory cytokine gene polymorphisms and circulating CD3 on long-term renal allograft outcome in Egyptian patients

SF El-Abd, NM Badr Eldin… - Immunological …, 2021 - Taylor & Francis
The extant study aimed to explore the influence of two cytokines TNF-α− 308 and IFN-γ+ 874
gene polymorphism on development of renal transplant rejection and to investigate the …