Extracellular matrix hydrogels from decellularized tissues: Structure and function

LT Saldin, MC Cramer, SS Velankar, LJ White… - Acta biomaterialia, 2017 - Elsevier
Extracellular matrix (ECM) bioscaffolds prepared from decellularized tissues have been
used to facilitate constructive and functional tissue remodeling in a variety of clinical …

Evolution of biomimetic ECM scaffolds from decellularized tissue matrix for tissue engineering: A comprehensive review

Y Zhang, C Zhang, Y Li, L Zhou, N Dan, J Min… - International Journal of …, 2023 - Elsevier
Tissue engineering is essentially a technique for imitating nature. Natural tissues are made
up of three parts: extracellular matrix (ECM), signaling systems, and cells. Therefore …

Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance

TJ Keane, IT Swinehart, SF Badylak - Methods, 2015 - Elsevier
Biologic scaffolds composed of extracellular matrix (ECM) are widely used in both preclinical
animal studies and in many clinical applications to repair and reconstruct tissues. Recently …

Extracellular matrix as an inductive scaffold for functional tissue reconstruction

BN Brown, SF Badylak - Translational Research, 2014 - Elsevier
The extracellular matrix (ECM) is a meshwork of both structural and functional proteins
assembled in unique tissue-specific architectures. The ECM both provides the mechanical …

Extracellular matrix as a biological scaffold material: Structure and function

SF Badylak, DO Freytes, TW Gilbert - Acta biomaterialia, 2009 - Elsevier
Biological scaffold materials derived from the extracellular matrix (ECM) of intact mammalian
tissues have been successfully used in a variety of tissue engineering/regenerative …

Extracellular matrix-based biomaterials and their influence upon cell behavior

MC Cramer, SF Badylak - Annals of biomedical engineering, 2020 - Springer
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

The extracellular matrix as a biologic scaffold material

SF Badylak - Biomaterials, 2007 - Elsevier
Biologic scaffolds composed of naturally occurring extracellular matrix (ECM) have received
significant attention for their potential therapeutic applications. The full potential of the ability …

Biodegradable elastomeric patch for treating cardiac or cardiovascular conditions

KL Fujimoto, K Tobita, J Guan, WR Wagner… - US Patent …, 2015 - Google Patents
2007-09-24 Assigned to UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH
SYSTEM OF HIGHER EDUCATION reassignment UNIVERSITY OF PITTSBURGH-OF THE …

Immune response to biologic scaffold materials

SF Badylak, TW Gilbert - Seminars in immunology, 2008 - Elsevier
Biologic scaffold materials composed of mammalian extracellular matrix are commonly used
in regenerative medicine and in surgical procedures for the reconstruction of numerous …

Preparation and rheological characterization of a gel form of the porcine urinary bladder matrix

DO Freytes, J Martin, SS Velankar, AS Lee, SF Badylak - Biomaterials, 2008 - Elsevier
Biologic scaffolds composed of extracellular matrix (ECM) have been used to facilitate the
repair and reconstruction of a variety of tissues in clinical and pre-clinical studies. The …