Determination of antioxidant, DNA protection, enzyme inhibition potential and molecular docking studies of a biomarker ursolic acid in Nepeta species
Ursolic acid (UA), which has many biological properties such as anti-cancer, anti-
inflammatory and antioxidant, and regulates some pharmacological processes, has been …
inflammatory and antioxidant, and regulates some pharmacological processes, has been …
A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase
Background Based on in vitro and in vivo rat experiments, the newly developed
acetylcholinesterase (AChE) reactivator, K203, appears to be much more effective in the …
acetylcholinesterase (AChE) reactivator, K203, appears to be much more effective in the …
Computer-aided drug discovery approaches against the tropical infectious diseases malaria, tuberculosis, trypanosomiasis, and leishmaniasis
Despite the tremendous improvement in overall global health heralded by the adoption of
the Millennium Declaration in the year 2000, tropical infections remain a major health …
the Millennium Declaration in the year 2000, tropical infections remain a major health …
Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to …
M Alagumuthu, S Arumugam - Bioorganic & Medicinal Chemistry, 2017 - Elsevier
Synthesis and molecular validation of 6-substituted-2-(3-phenoxyphenyl)-4-phenylquinoline
derivatives (4a-h) as antibacterial/DNA gyrase inhibitors reported. Primarily, 6-substituted-2 …
derivatives (4a-h) as antibacterial/DNA gyrase inhibitors reported. Primarily, 6-substituted-2 …
[HTML][HTML] New approaches to the development of anti-protozoan drug candidates: a review of patents
EFF da Cunha, TC Ramalho, DT Mancini… - Journal of the Brazilian …, 2010 - SciELO Brasil
Protozoan infections are parasitic diseases that affect hundreds of millions of people
worldwide, but have been largely neglected for drug development because they affect poor …
worldwide, but have been largely neglected for drug development because they affect poor …
Modification of benzoxazole derivative by bromine-spectroscopic, antibacterial and reactivity study using experimental and theoretical procedures
Abstract N-[2-(2-bromophenyl)-1, 3-benzoxazol-5-yl]-2-phenylacetamide (NBBPA) was
synthesized in this study as an original compound in order to evaluate its antibacterial …
synthesized in this study as an original compound in order to evaluate its antibacterial …
Applications of docking and molecular dynamic studies on the search for new drugs against the biological warfare agents Bacillus anthracis and Yersinia pestis
T Celmar Costa Franca… - … -Aided Drug Design, 2013 - ingentaconnect.com
The fear of biological warfare agents (BWA) use by terrorists is the major concern of the
security agencies and health authorities worldwide today. The non-existence of vaccines or …
security agencies and health authorities worldwide today. The non-existence of vaccines or …
Comparison of binding interactions of lomefloxacin to serum albumin and serum transferrin by resonance light scattering and fluorescence quenching methods
H Vahedian-Movahed, MR Saberi… - Journal of Biomolecular …, 2011 - Taylor & Francis
The interaction between lomefloxacin (LMF) and two drug carrier proteins, human serum
albumin (HSA) and serum transferrin (TF), were studied and compared by fluorescence …
albumin (HSA) and serum transferrin (TF), were studied and compared by fluorescence …
Potent inhibitor design against H1N1 swine influenza: structure-based and molecular dynamics analysis for M2 inhibitors from traditional Chinese medicine database
CH Lin, TT Chang, MF Sun, HY Chen… - Journal of …, 2011 - Taylor & Francis
The rapid spread of influenza virus subtype H1N1 poses a great threat to million lives
worldwide. To search for new anti-influenza compounds, we performed molecular docking …
worldwide. To search for new anti-influenza compounds, we performed molecular docking …
Investigations with spectroscopy, zeta potential and molecular modeling of the non-cooperative behaviour between cyclophosphamide hydrochloride and aspirin …
Z Omidvar, K Parivar, H Sanee… - Journal of …, 2011 - Taylor & Francis
The interaction between cyclophosphamide hydrochloride (CYC) and aspirin (ASA) with
human serum albumin (HSA) was studied by various kind of spectroscopic, ζ potential and …
human serum albumin (HSA) was studied by various kind of spectroscopic, ζ potential and …