ASCO Guidelines provide recommendations with comprehensive review and analyses of
the relevant literature for each recommendation, following the guideline development …

The standard of care in locally advanced rectal cancer is neoadjuvant chemoradiation
(nCRT) followed by radical surgery. Response to nCRT varies among patients and …

Colorectal carcinoma is one of the most common malignancies worldwide and the most
prevalent cause of cancer mortality in China. The Miles operation and permanent colostomy …

Objectives To measure the diagnostic performance of a new radiologic pattern on restaging
magnetic resonance (MR) high-resolution T2-weighted imaging (T2-WI)—the split scar sign …

Neoadjuvant chemoradiation (NCRT) followed by total mesorectal excision is the standard
treatment for locally advanced rectal cancer (LARC). To justify a non-surgical approach …

Background Overall survival from rectal cancer has almost doubled over the last 20 years.
Following recommendations in management guidelines plays some part in this, but the …

Background: MicroRNAs have altered expression levels in various diseases and may play
an important role in the diagnosis and prognosis of colorectal cancer (CRC). Methods: We …

Background With the well established shift to neoadjuvant treatment for locally advanced
rectal cancer, there is increasing focus on the use of radiosensitizers to improve the efficacy …

Abstract Introduction The Neoadjuvant rectal (NAR) score is a new surrogate endpoint to be
used in clinical trials for early determination of treatment response to different preoperative …

Background The management of rectal cancer has evolved considerably over the last few
decades with increasing use of neoadjuvant chemoradiotherapy (nCRT). Complete clinical …