Epigenetic mechanisms are processes that affect gene expression and cellular functions
without involving changes in the DNA sequence. This abnormal or unstable expression of …

Epigenetic regulation of gene transcription in the immune system is important for proper
control of protective and pathogenic inflammation. Aberrant epigenetic modifications are …

Aging is accompanied by homeostatic and functional dysregulation of multiple immune cell
subsets. Group 3 innate lymphoid cells (ILC3s) constitute a heterogeneous cell population …

Acute lung injury (ALI) is an inflammatory lung disease that is caused by bacterial infection.
Lipopolysaccharide (LPS), a prototype pathogen-associated molecular pattern (PAMP) from …

Isocorydine (ICD) is a type of isoquinoline alkaloid originating from Corydalis edulis, which
has been used to relieve spasm, dilate blood vessels, and treat malaria as well as hypoxia …

IL-6/STAT3 signaling is known to initiate the TH17 differentiation program, but the upstream
regulatory mechanisms remain minimally explored. Here, we show that Cxxc finger protein 1 …

Lepidoptera are a major source of pests in agriculture and forestry, investigating the immune
mechanisms of their model species, Bombyx mori, can provide valuable insights into …

Background & aim Gastric cancer (GC) is the third-leading cause of cancer-related deaths.
We established a prospective database of patients with GC who underwent surgical …

Cardiomyocyte maturation is the final stage of heart development, and abnormal
cardiomyocyte maturation will lead to serious heart diseases. CXXC zinc finger protein 1 …

CXXC Zinc finger protein 1 (CFP1) is a multitasking protein playing essential roles during
various developmental processes. Its ability to interact with several proteins contribute to …