Natural killer (NK) cells and natural killer T (NKT) cells are subsets of lymphocytes that share some phenotypical and functional similarities. Both cell types can rapidly respond to the …
M Tsuji, MS Nair, K Masuda, C Castagna… - Nature …, 2023 - nature.com
Prophylactic vaccines for SARS-CoV-2 have lowered the incidence of severe COVID-19, but emergence of viral variants that are antigenically distinct from the vaccine strains are of …
D Krijgsman, M Hokland, PJK Kuppen - Frontiers in immunology, 2018 - frontiersin.org
Natural killer T (NKT) cells are a subset of CD1d-restricted T cells at the interface between the innate and adaptive immune system. NKT cells can be subdivided into functional …
S Nair, MV Dhodapkar - Frontiers in immunology, 2017 - frontiersin.org
Natural killer T (NKT) cells are specialized CD1d-restricted T cells that recognize lipid antigens. Following stimulation, NKT cells lead to downstream activation of both innate and …
M Dougan, G Dranoff - Annual review of immunology, 2009 - annualreviews.org
Over the past decade, immune therapy has become a standard treatment for a variety of cancers. Monoclonal antibodies, immune adjuvants, and vaccines against oncogenic …
M Kronenberg - Annu. Rev. Immunol., 2005 - annualreviews.org
▪ Abstract Natural killer T (NKT) cells constitute a conserved T cell sublineage with unique properties, including reactivity for a synthetic glycolipid presented by CD1d, expression of an …
A Kurioka, LJ Walker, P Klenerman… - Clinical & translational …, 2016 - Wiley Online Library
The liver is an important immunological organ that remains sterile and tolerogenic in homeostasis, despite continual exposure to non‐self food and microbial‐derived products …
DI Godfrey, M Kronenberg - The Journal of clinical …, 2004 - Am Soc Clin Investig
NKT cells are a unique T lymphocyte sublineage that has been implicated in the regulation of immune responses associated with a broad range of diseases, including autoimmunity …
Cancer immunotherapy attempts to harness the exquisite power and specificity of the immune system for the treatment of malignancy. Although cancer cells are less …