Matrix metalloproteinases in normal pregnancy and preeclampsia

J Chen, RA Khalil - Progress in molecular biology and translational …, 2017 - Elsevier
Normal pregnancy is associated with marked hemodynamic and uterine changes that allow
adequate uteroplacental blood flow and uterine expansion for the growing fetus. These …

Vascular mechanisms and molecular targets in hypertensive pregnancy and preeclampsia

H Qu, RA Khalil - American Journal of Physiology-Heart and …, 2020 - journals.physiology.org
Preeclampsia is a major complication of pregnancy manifested as hypertension and often
intrauterine growth restriction, but the underlying pathophysiological mechanisms are …

Mechanisms of endothelial dysfunction in hypertensive pregnancy and preeclampsia

JS Possomato-Vieira, RA Khalil - Advances in pharmacology, 2016 - Elsevier
Preeclampsia is a pregnancy-related disorder characterized by hypertension and could lead
to maternal and fetal morbidity and mortality. Although the causative factors and …

Bioactive factors in uteroplacental and systemic circulation link placental ischemia to generalized vascular dysfunction in hypertensive pregnancy and preeclampsia

DA Shah, RA Khalil - Biochemical pharmacology, 2015 - Elsevier
Preeclampsia is a pregnancy-associated disorder characterized by hypertension, and could
lead to maternal and fetal morbidity and mortality; however, the pathophysiological …

Magnesium in pregnancy

LM Dalton, DM Ní Fhloinn, GT Gaydadzhieva… - Nutrition …, 2016 - academic.oup.com
Magnesium deficiency is prevalent in women of childbearing age in both developing and
developed countries. The need for magnesium increases during pregnancy, and the …

Maternal nutritional risk factors for pre-eclampsia incidence: findings from a narrative scoping review

MLW Kinshella, S Omar, K Scherbinsky, M Vidler… - Reproductive health, 2022 - Springer
Background Pre-eclampsia is a leading cause of maternal mortality and morbidity that
involves pregnancy-related stressors on the maternal cardiovascular and metabolic …

Magnesium deficiency and cardiometabolic disease

R Fritzen, A Davies, M Veenhuizen, M Campbell… - Nutrients, 2023 - mdpi.com
Magnesium (Mg2+) has many physiological functions within the body. These include
important roles in maintaining cardiovascular functioning, where it contributes to the …

Association of dietary calcium intake, total and ionized serum calcium levels with preeclampsia in Ethiopia

RD Gebreyohannes, A Abdella, W Ayele… - BMC pregnancy and …, 2021 - Springer
Background Preeclampsia is a well-known cause of maternal mortality and morbidity in
Ethiopia. The exact pathophysiology has not been fully understood. Calcium and …

Serum magnesium and calcium in preeclampsia: a comparative study at the Korle-Bu Teaching Hospital, Ghana

E Owusu Darkwa, C Antwi-Boasiako… - Integrated blood …, 2017 - Taylor & Francis
Background A large percentage (16% of maternal mortality in developed countries,
compared to 9% in developing countries), is due to hypertensive disorders in pregnancy …

Serum magnesium levels in preterm infants are higher than adult levels: a systematic literature review and meta-analysis

J Rigo, C Pieltain, V Christmann, F Bonsante, SJ Moltu… - Nutrients, 2017 - mdpi.com
Magnesium (Mg) is an essential mineral in the body, impacting the synthesis of
biomacromolecules, bone matrix development, energy production, as well as heart, nerve …