Bone fractures are common occurrence in clinical settings, creating a high demand for
effective repair material. Unfortunately, limited graft availability, donor site morbidities …

The use of tissue engineering to restore and to build new bone tissue is under active
research at present. The following review summarizes the latest studies and clinical trials …

Metabolic abnormalities, such as diabetes mellitus and obesity, can impact bone quantity
and/or bone quality. In this work, we characterize bone material properties, in terms of …

Abstract Purpose of Review This review aims to provide a theoretical basis and insights for
quercetin's clinical application in the prevention and treatment of osteoporosis (OP) …

Many biological fibrous tissues exhibit distinctive mechanical properties arising from their
highly organized fibrous structure. In disease conditions, alterations in the primary …

Abstract Purpose of Review Metabolic and genetic bone disorders affect not only bone mass
but often also the bone material, including degree of mineralization, matrix organization, and …

There is no cure for osteogenesis imperfecta (OI), and current treatments can only partially
correct the bone phenotype. Stem cell therapy holds potential to improve bone quality and …

About 70% of people with osteogenesis imperfecta (OI) experience hearing loss. There is no
cure for OI, and therapies to ameliorate hearing loss rely on conventional treatments for …

Tissue engineering is an interdisciplinary science that exploits most branches of science
from chemistry, biology, and engineering to achieve its desired goal of tissue regeneration …

Healthy bone has the ability to resist deformation and fracture, while adapting to applied
mechanical loads. These properties of bone depend on characteristics of its extracellular …