The structural and functional role of RNA in icosahedral virus assembly

A Schneemann - Annu. Rev. Microbiol., 2006 - annualreviews.org
Despite tremendous advances in high-resolution structure determination of virus particles,
the organization of encapsidated genomes and their role during assembly are poorly …

A novel delivery platform based on Bacteriophage MS2 virus-like particles

Y Fu, J Li - Virus Research, 2016 - Elsevier
Our objective here is to review the novel delivery platform based on Bacteriophage MS2
virus-like particles (VLPs), including introduction to their structure, their potential as a …

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins

SM Lok, V Kostyuchenko, GE Nybakken… - Nature structural & …, 2008 - nature.com
The monoclonal antibody 1A1D-2 has been shown to strongly neutralize dengue virus
serotypes 1, 2 and 3, primarily by inhibiting attachment to host cells. A crystal structure of its …

Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ

RI Koning, J Gomez-Blanco, I Akopjana… - Nature …, 2016 - nature.com
In single-stranded ribonucleic acid (RNA) viruses, virus capsid assembly and genome
packaging are intertwined processes. Using cryo-electron microscopy and single particle …

[HTML][HTML] Impact of chemical and structural anisotropy on the electrophoretic mobility of spherical soft multilayer particles: the case of bacteriophage MS2

J Langlet, F Gaboriaud, C Gantzer, JFL Duval - Biophysical journal, 2008 - cell.com
We report a theoretical investigation of the electrohydrodynamic properties of spherical soft
particles composed of permeable concentric layers that differ in thickness, soft material …

A simple, RNA-mediated allosteric switch controls the pathway to formation of a T= 3 viral capsid

PG Stockley, O Rolfsson, GS Thompson… - Journal of molecular …, 2007 - Elsevier
Using mass spectrometry we have detected both assembly intermediates and the final
product, the T= 3 viral capsid, during reassembly of the RNA bacteriophage MS2. Assembly …

Virus removal and inactivation mechanisms during iron electrocoagulation: capsid and genome damages and electro-Fenton reactions

K Kim, J Narayanan, A Sen… - Environmental Science & …, 2021 - ACS Publications
Virus destabilization and inactivation are critical considerations in providing safe drinking
water. We demonstrate that iron electrocoagulation simultaneously removed (via sweep …

The three-dimensional structure of genomic RNA in bacteriophage MS2: implications for assembly

K Toropova, G Basnak, R Twarock, PG Stockley… - Journal of molecular …, 2008 - Elsevier
Using cryo-electron microscopy, single particle image processing and three-dimensional
reconstruction with icosahedral averaging, we have determined the three-dimensional …

Asymmetric cryo-EM structure of the canonical Allolevivirus Qβ reveals a single maturation protein and the genomic ssRNA in situ

KV Gorzelnik, Z Cui, CA Reed… - Proceedings of the …, 2016 - National Acad Sciences
Single-stranded (ss) RNA viruses infect all domains of life. To date, for most ssRNA virions,
only the structures of the capsids and their associated protein components have been …

The true story and advantages of RNA phage capsids as nanotools

P Pumpens, R Renhofa, A Dishlers, T Kozlovska… - Intervirology, 2016 - karger.com
RNA phages are often used as prototypes for modern recombinant virus-like particle (VLP)
technologies. Icosahedral RNA phage VLPs can be formed from coat proteins (CPs) and are …