The therapeutic potential and clinical significance of exosomes as carriers of drug delivery system

T Li, X Li, G Han, M Liang, Z Yang, C Zhang, S Huang… - Pharmaceutics, 2022 - mdpi.com
Drug delivery system (DDS) realizes the drug delivery process through the drug carrier. As
an important part of DDS, the selection of the drug carrier material is extremely critical, which …

[HTML][HTML] Exosomes as drug delivery systems: endogenous nanovehicles for treatment of systemic lupus erythematosus

A Ortega, O Martinez-Arroyo, MJ Forner, R Cortes - Pharmaceutics, 2021 - mdpi.com
Exosomes, nanometer-sized lipid-bilayer-enclosed extracellular vesicles (EVs), have
attracted increasing attention due to their inherent ability to shuttle proteins, lipids and genes …

Advancements in rheumatoid arthritis therapy: a journey from conventional therapy to precision medicine via nanoparticles targeting immune cells

A Laha, S Nasra, D Bhatia, A Kumar - Nanoscale, 2024 - pubs.rsc.org
Rheumatoid arthritis (RA) is a progressive autoimmune disease that mainly affects the inner
lining of the synovial joints and leads to chronic inflammation. While RA is not known as …

Organic and biogenic nanocarriers as bio-friendly systems for bioactive compounds' delivery: state-of-the art and challenges

SM Petrovic, ME Barbinta-Patrascu - Materials, 2023 - mdpi.com
“Green” strategies to build up novel organic nanocarriers with bioperformance are modern
trends in nanotechnology. In this way, the valorization of bio-wastes and the use of living …

Cell-derived nanovesicles from mesenchymal stem cells as extracellular vesicle-mimetics in wound healing

YR Neupane, HK Handral, SA Alkaff, WH Chng… - … Pharmaceutica Sinica B, 2023 - Elsevier
Wound healing is a dynamic process that involves a series of molecular and cellular events
aimed at replacing devitalized and missing cellular components and/or tissue layers …

Lipid nanoparticulate drug delivery systems: recent advances in the treatment of skin disorders

SR Stefanov, VY Andonova - Pharmaceuticals, 2021 - mdpi.com
The multifunctional role of the human skin is well known. It acts as a sensory and immune
organ that protects the human body from harmful environmental impacts such as chemical …

Hyaluronate-functionalized hydroxyapatite nanoparticles laden with methotrexate and teriflunomide for the treatment of rheumatoid arthritis

S Pandey, N Rai, A Mahtab, D Mittal, FJ Ahmad… - International Journal of …, 2021 - Elsevier
Rheumatoid arthritis (RA), an autoimmune inflammatory disorder is currently incurable.
Methotrexate and Teriflunomide are routinely prescribed drugs but their uses are limited due …

Facile functionalization of Teriflunomide-loaded nanoliposomes with Chondroitin sulphate for the treatment of Rheumatoid arthritis

A Mahtab, SA Rabbani, YR Neupane, S Pandey… - Carbohydrate …, 2020 - Elsevier
This research aims to coat Teriflunomide (TEF) loaded conventional nanoliposomes (CON-
TEF-LIPO) with Chondroitin sulphate (CS) to produce CS-TEF-LIPO for the effective …

Recent advances in targeted nanotherapeutic approaches for breast cancer management

P Gupta, YR Neupane, S Parvez, K Kohli - Nanomedicine, 2021 - Taylor & Francis
Breast cancer is the most commonly occurring tumor disease worldwide. Breast cancer is
currently managed by conventional chemotherapy, which is inadequate in curbing this …

QbD-Driven preparation, characterization, and pharmacokinetic investigation of daidzein-l oaded nano-cargos of hydroxyapatite

N Gautam, D Dutta, S Mittal, P Alam, NA Emad… - Scientific Reports, 2025 - nature.com
The repercussions of hormone replacement therapy (HRT) and bisphosphonates pose
serious clinical challenges and warrant novel therapies for osteoporosis in menopausal …