In the drug delivery field, there is beyond doubt that the shape of micro-and nanoparticles
(M&NPs) critically affects their biological fate. Herein, following an introduction describing …

Cancer can be defined as an irregular functioning of the cell cycle that results in a
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …

Recently, the interest in the application of cell viability assays has been increasing in various
fields. Cell viability assays may be broadly classified as (a) dye exclusion assays,(b) …

This study aimed to develop risk scores based on clinical characteristics at presentation to
predict intensive care unit (ICU) admission and mortality in COVID-19 patients. 641 …

Sulfonamides are among the most promising potential inhibitors for carbonic anhydrases
(CAs), which are pharmaceutically relevant targets for treating several disease conditions …

Background Mitochondrial DNA (MT-DNA) are intrinsically inflammatory nucleic acids
released by damaged solid organs. Whether circulating cell-free MT-DNA quantitation could …

Not long after plastic-made material became an inseparable part of our lives, microplastics
(MPs) found their way into ecosystems. Aquatic organisms are one of the groups impacted …

Background COVID-19 pandemic has developed rapidly and the ability to stratify the most
vulnerable patients is vital. However, routinely used severity scoring systems are often low …

Acyl-CoA synthetase long-chain family member 4 (ACSL4) is a member of the long chain
family of acyl-CoA synthetase proteins, which have recently been shown to serve an …

In the present medical epoch, the prevailing approach of drug discovery, which focuses on
inhibiting a single target, has been superseded by the concept of designing drugs that target …