Snakebite envenoming is a pathological condition which may occur in response to the
injection of venom. Snake venoms contain a complex mixture of biologically active …

Envenomation by viperid snakes is characterized by systemic thrombotic syndrome and
prominent local inflammation. To date, the mechanisms underlying inflammation and blood …

INTRODUCTION Brazil has the largest number of snakebite cases in South America, of
which the large majority is concentrated in the Midwest and North. METHODS In this …

Polymorphonuclear neutrophils are the most abundant leukocytes in the blood and
constitute key components of the innate immunity. Upon infection or tissue damage …

Literature shows that phospholipases A 2 isolated from snake venoms of the genus
Bothrops are involved in the local inflammatory response. However, the mechanisms by …

Background: Snake venom phospholipases A2 (PLA2s) have hemolytic, anticoagulant,
myotoxic, oedematogenic, bactericidal, and inflammatory actions. BthTX-I, a Lys49-PLA2 …

Bothrops mattogrossensis snake is widely distributed throughout eastern South America and
is responsible for snakebites in this region. This paper reports the purification and …

Increased vascular permeability is a frequent outcome of viperid snakebite envenomation,
leading to local and systemic complications. We reported that snake venom cysteine-rich …

In the present study, we investigated the in vitro effects of two basic myotoxic
phospholipases A2 (PLA2), BaTX‐I, a catalytically inactive Lys‐49 variant, and BaTX‐II, a …

The aim of the study was to evaluate the in vitro effects of Bothrops bilineata crude venom
(BbV) on isolated human neutrophil function. We proved that BbV isn't toxic towards human …