A variety of radioiodination methods is available in the literature depending upon the nature
of organic compound to be labeled, however only few can completely fulfill manufacturing …

Improving urinary bladder cancer diagnosis, follow-up, and therapy tools to overcome
existing limitations and increase survival rates is a highly desirable goal. In the current …

Gemcitabine (GEM) is a powerful anticancer drug for various cancers. However, the
anticancer efficacy and the side effects should be addressed for effective therapeutics. To …

Brain cancer is a challenging disease to treat using conventional approaches. The present
investigation aimed to develop a radiopharmaceutical targeting brain cancer based on …

Purpose The present investigation aims to develop and evaluate a radiopharmaceutical for
targeting and assessing β-cells mass based on gliclazide, an antidiabetic drug that …

Hepatocellular carcinoma is a widely prevalent cancer, and hence, the development of
radiopharmaceuticals for its management is an important issue. In the current investigation …

Avanafil, a selective second-generation phosphodiesterase-5 inhibitor, was successfully
labeled with iodine-125 via electrophilic and different factors affecting the labeling efficiency …

In this study, the optimization of troxacitabine labeling with iodine‐125 and its biological
evaluation were described. Troxacitabine was labeled via direct electrophilic substitution …

Tritium radiopharmaceuticals are often used in drug development because of their desirable
specific activity. The inherent instability of these radioactive tracers often leads to a …

Gemcitabine (gem) is a nucleoside analog that is used to treat pancreatic cancers (PaCa),
which have dismal prognosis and low survival rate. Though gem is used as first line of …