Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Hydrogen Sulfide: An Emerging Regulator of Oxidative Stress and Cellular Homeostasis—A Comprehensive One-Year Review

C Munteanu, MA Turnea, M Rotariu - Antioxidants, 2023 - mdpi.com
Hydrogen sulfide (H2S), traditionally recognized as a toxic gas, has emerged as a critical
regulator in many biological processes, including oxidative stress and cellular homeostasis …

The role of hydrogen sulfide in regulation of cell death following neurotrauma and related neurodegenerative and psychiatric diseases

S Rodkin, C Nwosu, A Sannikov, M Raevskaya… - International Journal of …, 2023 - mdpi.com
Injuries of the central (CNS) and peripheral nervous system (PNS) are a serious problem of
the modern healthcare system. The situation is complicated by the lack of clinically effective …

VEGF signaling: Role in angiogenesis and beyond

P Shaw, SKD Dwivedi, R Bhattacharya… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Angiogenesis is a crucial process for tissue development, repair, and tumor survival.
Vascular endothelial growth factor (VEGF) is a key driver secreted by cancer cells …

Recent therapeutic approaches to cystathionine beta‐synthase‐deficient homocystinuria

T Majtan, V Kožich, WD Kruger - British journal of …, 2023 - Wiley Online Library
Cystathionine beta‐synthase (CBS)‐deficient homocystinuria (HCU) is the most common
inborn error of sulfur amino acid metabolism. The pyridoxine non‐responsive form of the …

[HTML][HTML] Autophagy and mitophagy as potential therapeutic targets in diabetic heart condition: Harnessing the power of nanotheranostics

S Nag, O Mitra, B Maturi, SP Kaur, A Saini… - Asian Journal of …, 2024 - Elsevier
Autophagy and mitophagy pose unresolved challenges in understanding the pathology of
diabetic heart condition (DHC), which encompasses a complex range of cardiovascular …

Cellular turnover and degradation of the most common missense cystathionine beta‐synthase variants causing homocystinuria

E Mijatovic, K Ascenção, C Szabo, T Majtan - Protein Science, 2024 - Wiley Online Library
Homocystinuria (HCU) due to cystathionine beta‐synthase (CBS) deficiency is the most
common inborn error of sulfur amino acid metabolism. Recent work suggests that missense …

A high-performance dual-modal probe boosted by pKa manipulation for colorimetric and fluorescent detection of hydrogen sulfide in living cells and food spoilage

F Chu, B Feng, M Liu, M Liu, F Chen, J Dong, W Zeng - Dyes and Pigments, 2024 - Elsevier
Since hydrogen sulfide (H 2 S) plays a vital role in physiological functions, it is significant to
assess the dynamic levels of H 2 S in cellular levels and real samples. Nonetheless, a …

Role of cystathionine β-synthase and 3-mercaptopyruvate sulfurtransferase in the regulation of proliferation, migration, and bioenergetics of murine breast cancer cells

SS Santos, LOCP Rodrigues, V Martins, M Petrosino… - Antioxidants, 2023 - mdpi.com
Cystathionine β-synthase (CBS), CSE (cystathionine γ-lyase) and 3-mercaptopyruvate
sulfurtransferase (3-MST) have emerged as three significant sources of hydrogen sulfide …

[HTML][HTML] Epigallocatechin gallate is a potent inhibitor of cystathionine beta-synthase: Structure-activity relationship and mechanism of action

K Zuhra, M Petrosino, B Gupta, T Panagaki, M Cecconi… - Nitric Oxide, 2022 - Elsevier
Epigallocatechin gallate (EGCG) is the main bioactive component of green tea. Through
screening of a small library of natural compounds, we discovered that EGCG inhibits …