Impaired JAK-STAT pathway signaling in leukocytes of the frail elderly

LD Samson, P Engelfriet, WMM Verschuren… - Immunity & …, 2022 - Springer
Background Elderly often show reduced immune functioning and can develop chronic low-
grade inflammation. Why some elderly are more prone to become frail is unknown. We …

Association among terminally differentiated T cells, frailty, and dependency in a group of Cuban centenarians

AL Añé-Kourí, N Ledón, MB Ramos, A González… - Gerontology, 2023 - karger.com
Introduction: Centenarians are considered a model of successful aging. Cuba exhibits one
of the oldest populations in Latin America with more than two thousand centenarians …