Research progress and applications of multivalent, multispecific and modified nanobodies for disease treatment

J Wang, G Kang, H Yuan, X Cao, H Huang… - Frontiers in …, 2022 - frontiersin.org
Recombinant antibodies such as nanobodies are progressively demonstrating to be a valid
alternative to conventional monoclonal antibodies also for clinical applications. Furthermore …

Early diagnosis of symptomatic ovarian cancer in primary care in the UK: opportunities and challenges

S Rampes, SP Choy - Primary Health Care Research & Development, 2022 - cambridge.org
Background: Ovarian cancer is the sixth most common cause of cancer-related death in the
UK amongst women. Ovarian cancer presents particular challenges for general practitioners …

A nomogram model based on clinical markers for predicting malignancy of ovarian tumors

B Gao, X Zhao, P Gu, D Sun, X Liu, W Li… - Frontiers in …, 2022 - frontiersin.org
Objective The aim of this study was to build a nomogram based on clinical markers for
predicting the malignancy of ovarian tumors (OTs). Method A total of 1,268 patients …

The results of personificated ovarian cancer patients with peritoneal carcinomatosis treatment

AI Рибін - Репродуктивне здоров'я жінки, 2022 - repro-health.com.ua
Materials and methods. 119 patients with ovarian cancer of the IIIC stage were involved into
the study from 2013 to 2020 and they were treated at the University Clinic of Odessa …

Overexpression of NPTX2 Promotes Malignant Phenotype of Epithelial Ovarian Carcinoma via IL6-JAK2/STAT3 Signaling Pathway Under Hypoxia

X Han, Y Lu, X Li, L Xia, H Wen, Z Feng, X Ju… - Frontiers in …, 2021 - frontiersin.org
Background Epithelial ovarian cancer (EOC) is the main subtype of ovarian cancer and
shows an aggressive phenotype and poor prognosis. Neuronal pentraxin II (NPTX2) is a …

[PDF][PDF] Risk prediction models for symptomatic patients with bladder and kidney cancer: a systematic review

H Harrison, JA Usher-Smith, L Li, LE Roberts… - British Journal of …, 2021 - bjgp.org
Background Timely diagnosis of bladder and kidney cancer is key to improving clinical
outcomes. Given the challenges of early diagnosis, models incorporating clinical symptoms …

[HTML][HTML] Cancer incidence and competing mortality risk following 15 presenting symptoms in primary care: a population-based cohort study using electronic healthcare …

ME Barclay, C Renzi, H Harrison, A Torralbo… - BMJ …, 2024 - pmc.ncbi.nlm.nih.gov
Objectives Assessment of age, sex and smoking-specific risk of cancer diagnosis and non-
cancer mortality following primary care consultation for 15 new-onset symptoms. Methods …

MiR-92a regulates PTEN/Akt signaling axis to promote paclitaxel resistance in ovarian cancer cells

X Deng, H Wu, L Xiong, M Wu, J Cao… - Acta Biochimica …, 2023 - abp.ptbioch.edu.pl
To investigate the function and possible mechanism of miR-92a in malignant behaviors such
as paclitaxel resistance in ovarian cancer (OC) cells. The miR-92a and PTEN expression …

[HTML][HTML] Modified HE4, CA125, and ROMA cut-off values and predicted probability of ovarian tumor in Chinese patients

X Zhao, M Zhao, B Gao, A Zhang, D Xu - Gland Surgery, 2021 - ncbi.nlm.nih.gov
Background Most prior studies investigating the risk of ovarian malignancy algorithm
(ROMA) with cancer antigen 125 (CA125) and human epididymis protein 4 (HE4) have …

Pain nursing for gynecologic cancer patients

W Wu, X He, S Li, M Jin, Y Ni - Frontiers in Oncology, 2023 - frontiersin.org
Gynecological malignancy remains a prevalent cause of mortality among women. Chronic
cancer pain, as a severe complication of malignancy and its therapies, accounts for a …