Per-and polyfluoroalkyl substances (PFAS) are highly persistent, manufactured chemicals
used in various manufacturing processes and found in numerous commercial products. With …

Because undesirable pharmacokinetics and toxicity are significant reasons for the failure of
drug development in the costly late stage, it has been widely recognized that drug ADMET …

Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluoroalkyl substances (PFAS s) in food. Based …

Associations between per-and polyfluoroalkyl substances (PFASs) and increased blood
lipids have been repeatedly observed in humans, but a causal relation has been debated …

Humans are exposed to complex mixtures of per-and polyfluoroalkyl substances (PFAS).
However, human health risk assessment of PFAS currently relies on animal toxicity data …

Toxicokinetics are important for extrapolating health effects and effect levels observed in
laboratory animals to humans for purposes of establishing health-based criteria. We …

Per-and polyfluoroalkyl substances (PFAS) are a group of persistent environmental
pollutants that are ubiquitously found in the environment and virtually in all living organisms …

Background Considerable attention has been paid to perfluoroalkyl compounds (PFCs)
because of their worldwide presence in humans, wildlife, and environment. A wide variety of …

Per-and polyfluoroalkyl substances (PFAS), dubbed “forever chemicals”, are widely present
in the environment. Environmental contamination and food contact substances are the main …

Per-and polyfluoroalkyl substances (PFAS) are a class of artificially synthetic organic
compounds that are hardly degraded in the natural environment. PFAS have been widely …