Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic

A Hasankhani, A Bahrami, N Sheybani, B Aria… - Frontiers in …, 2021 - frontiersin.org
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …

Improving beef progeny performance through developmental programming

P Moriel, EA Palmer, KM Harvey… - Frontiers in Animal …, 2021 - frontiersin.org
Maternal nutritional management during gestation appears to modulate fetal development
and imprint offspring postnatal health and performance, via altered organ and tissue …

Maternal diet induces persistent DNA methylation changes in the muscle of beef calves

R Amorín, L Liu, P Moriel, N DiLorenzo… - Scientific Reports, 2023 - nature.com
Maternal nutrition during pregnancy can induce epigenetic alterations in the fetal genome,
such as changes in DNA methylation. It remains unclear whether these epigenetic …

Integrated network analysis to identify key modules and potential hub genes involved in bovine respiratory disease: A systems biology approach

A Hasankhani, A Bahrami, N Sheybani, F Fatehi… - Frontiers in …, 2021 - frontiersin.org
Background: Bovine respiratory disease (BRD) is the most common disease in the beef and
dairy cattle industry. BRD is a multifactorial disease resulting from the interaction between …

One-carbon metabolite supplementation to heifers for the first 14 d of the estrous cycle alters the plasma and hepatic one-carbon metabolite pool and methionine …

MS Crouse, HC Freetly… - Journal of Animal …, 2023 - academic.oup.com
The objective of this study was to determine the dose of folate and vitamin B12 in beef
heifers fed rumen protected methionine and choline required to maintain increased B12 …

Timing of maternal supplementation of dried distillers grains during late gestation influences postnatal growth, immunocompetence, and carcass characteristics of Bos …

EA Palmer, M Vedovatto, RA Oliveira… - Journal of Animal …, 2022 - academic.oup.com
This 2-yr study investigated the timing of dried distillers grains (DDG) supplementation
during the third trimester of gestation of Bos indicus-influenced beef cows and its impact on …

Maternal methionine supplementation during gestation alters alternative splicing and DNA methylation in bovine skeletal muscle

L Liu, R Amorín, P Moriel, N DiLorenzo, PA Lancaster… - BMC genomics, 2021 - Springer
Background The evaluation of alternative splicing, including differential isoform expression
and differential exon usage, can provide some insights on the transcriptional changes that …

[HTML][HTML] Benchmarking DNA methylation analysis of 14 alignment algorithms for whole genome bisulfite sequencing in mammals

W Gong, X Pan, D Xu, G Ji, Y Wang, Y Tian… - Computational and …, 2022 - Elsevier
Whole genome bisulfite sequencing (WGBS) is an essential technique for methylome
studies. Although a series of tools have been developed to overcome the mapping …

Rumen‐protected methionine modulates body temperature and reduces the incidence of heat stress temperatures during the hottest hours of the day of grazing heat …

VS Izquierdo, B da Silva Menezes… - Animal Science …, 2024 - Wiley Online Library
This study evaluated the effects of supplementation of rumen‐protected methionine (RPM)
on body thermoregulation and conception rate of Nelore cows exposed to high temperature …

Effects of maternal gestational diet, with or without methionine, on muscle transcriptome of Bos indicus-influenced beef calves following a vaccine-induced …

EA Palmer, F Peñagaricano, M Vedovatto… - PLoS …, 2021 - journals.plos.org
Maternal nutrition during gestation can cause epigenetic effects that translate to alterations
in gene expression in offspring. This 2-year study employed RNA-sequencing technology to …