Patterned control of human locomotion

F Lacquaniti, YP Ivanenko, M Zago - The Journal of physiology, 2012 - Wiley Online Library
There is much experimental evidence for the existence of biomechanical constraints which
simplify the problem of control of multi‐segment movements. In addition, it has been …

Early identification and intervention in cerebral palsy

A Herskind, G Greisen… - Developmental Medicine & …, 2015 - Wiley Online Library
Infants with possible cerebral palsy (CP) are commonly assumed to benefit from early
diagnosis and early intervention, but substantial evidence for this is lacking. There is no …

The motor cortex drives the muscles during walking in human subjects

TH Petersen, M Willerslev‐Olsen… - The Journal of …, 2012 - Wiley Online Library
Key points• It is often assumed that automatic movements such as walking require little
conscious attention and it has therefore been argued that these movements require little …

Development of human locomotion

F Lacquaniti, YP Ivanenko, M Zago - Current opinion in neurobiology, 2012 - Elsevier
Neural control of locomotion in human adults involves the generation of a small set of basic
patterned commands directed to the leg muscles. The commands are generated …

Gait training facilitates central drive to ankle dorsiflexors in children with cerebral palsy

M Willerslev-Olsen, TH Petersen, SF Farmer… - Brain, 2015 - academic.oup.com
Foot drop and toe walking are frequent concerns in children with cerebral palsy. The main
underlying cause of these problems is early damage and lack of maturation of the …

Dynamics of corticospinal motor control during overground and treadmill walking in humans

L Roeder, TW Boonstra, SS Smith… - Journal of …, 2018 - journals.physiology.org
Increasing evidence suggests cortical involvement in the control of human gait. However,
the nature of corticospinal interactions remains poorly understood. We performed time …

Decrease in force steadiness with aging is associated with increased power of the common but not independent input to motor neurons

AM Castronovo, N Mrachacz-Kersting… - Journal of …, 2018 - journals.physiology.org
Declines in motor function with advancing age have been attributed to changes occurring at
all levels of the neuromuscular system. However, the impact of aging on the control of …

Corticospinal control of normal and visually guided gait in healthy older and younger adults

ME Spedden, JT Choi, JB Nielsen, SS Geertsen - Neurobiology of aging, 2019 - Elsevier
We investigated age-related differences in corticospinal control of muscle activity during
normal and visually guided (VG) walking. Young (n= 15, 22.1±1.7 years) and older (n= 15 …

Involvement of the corticospinal tract in the control of human gait

D Barthélemy, MJ Grey, JB Nielsen, L Bouyer - Progress in brain research, 2011 - Elsevier
Given the inherent mechanical complexity of human bipedal locomotion, and that complete
spinal cord lesions in human leads to paralysis with no recovery of gait, it is often suggested …

Reorganization of functional and directed corticomuscular connectivity during precision grip from childhood to adulthood

MM Beck, ME Spedden, J Lundbye-Jensen - Scientific Reports, 2021 - nature.com
How does the neural control of fine movements develop from childhood to adulthood? Here,
we investigated developmental differences in functional corticomuscular connectivity using …