Curcumin and inflammatory bowel disease: potential and limits of innovative treatments

L Vecchi Brumatti, A Marcuzzi, PM Tricarico, V Zanin… - Molecules, 2014 - mdpi.com
Curcumin belongs to the family of natural compounds collectively called curcuminoids and it
possesses remarkable beneficial anti-oxidant, anti-inflammatory, anti-cancer, and …

[HTML][HTML] Optimization of the treatment with immunosuppressants and biologics in inflammatory bowel disease

S Renna, M Cottone, A Orlando - World Journal of …, 2014 - ncbi.nlm.nih.gov
Many placebo controlled trials and meta-analyses evaluated the efficacy of different drugs
for the treatment of inflammatory bowel disease (IBD), including immunosuppressants and …

Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease

FM Ruemmele, G Veres, KL Kolho… - Journal of Crohn's …, 2014 - academic.oup.com
Children and adolescents with Crohn's disease (CD) present often with a more complicated
disease course compared to adult patients. In addition, the potential impact of CD on growth …

Effect of thalidomide on clinical remission in children and adolescents with refractory Crohn disease: a randomized clinical trial

M Lazzerini, S Martelossi, G Magazzù, S Pellegrino… - Jama, 2013 - jamanetwork.com
Importance Pediatric-onset Crohn disease is more aggressive than adult-onset disease, has
high rates of resistance to existing drugs, and can lead to permanent impairments. Few trials …

Systematic review: thalidomide and thalidomide analogues for treatment of inflammatory bowel disease

C Yang, P Singh, H Singh, ML Le… - Alimentary …, 2015 - Wiley Online Library
Background It has been reported that thalidomide may be effective in treating inflammatory
bowel disease (IBD). Aim To review the evidence examining the efficacy and safety of …

Thalidomide for inflammatory bowel disease: Systematic review

M Bramuzzo, A Ventura, S Martelossi, M Lazzerini - Medicine, 2016 - journals.lww.com
Background: Thalidomide is an immunomodulatory drug used in the experimental treatment
of refractory Crohn disease and ulcerative colitis. We aimed to review the existing evidence …

Anxiety symptoms and disease severity in children and adolescents with Crohn disease

LC Reigada, CJ Hoogendoorn, LC Walsh… - Journal of Pediatric …, 2015 - journals.lww.com
Objectives: Children and adolescents diagnosed as having Crohn disease (CD), a type of
inflammatory bowel disease (IBD), have increased vulnerability for anxiety symptoms that …

Recent insights into the molecular pathogenesis of Crohn's disease: a review of emerging therapeutic targets

TEM Manuc, MM Manuc… - Clinical and experimental …, 2016 - Taylor & Francis
Chronic inflammatory bowel diseases (IBDs) are a subject of great interest in
gastroenterology, due to a pathological mechanism that is difficult to explain and an optimal …

A cross-sectional study on malnutrition in inflammatory bowel disease: is there a difference based on pediatric or adult age grouping?

V Marcil, E Levy, D Amre, A Bitton… - Inflammatory bowel …, 2019 - academic.oup.com
Background Malnutrition, commonly observed in inflammatory bowel disease (IBD), is
associated with increased morbidity and mortality and is attributed to multiple causes. The …

Review of thalidomide use in the pediatric population

CS Yang, C Kim, RJ Antaya - Journal of the American Academy of …, 2015 - Elsevier
Thalidomide is resurging in the management of adult rheumatologic skin conditions,
especially lupus erythematosus. Although use in pediatric patients is reported since the …