[HTML][HTML] Membrane interactions of phytochemicals as their molecular mechanism applicable to the discovery of drug leads from plants

H Tsuchiya - Molecules, 2015 - mdpi.com
In addition to interacting with functional proteins such as receptors, ion channels, and
enzymes, a variety of drugs mechanistically act on membrane lipids to change the …

[HTML][HTML] Electrochemical sensors and biosensors for the determination of diclofenac in pharmaceutical, biological and water samples

W Boumya, N Taoufik, M Achak, H Bessbousse… - Talanta Open, 2021 - Elsevier
Diclofenac is a non-steroidal anti-inflammatory drug of wide use around the world for the
treatment of several diseases such as ankylosing spondylitis, acute muscle pain conditions …

[HTML][HTML] Modified biochar from Moringa seed powder for the removal of diclofenac from aqueous solution

A Bagheri, E Abu-Danso, J Iqbal… - Environmental Science and …, 2020 - Springer
In this study, Moringa seed powder (M SP) was pyrolyzed at 450° C to synthesize Moringa
seed powder biochar (M SP B) and treated with phosphoric acid (H 3 PO 4) to synthesize …

Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine

LM Lichtenberger, Y Zhou, V Jayaraman… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most widely consumed
pharmaceuticals, yet both the mechanisms involved in their therapeutic actions and side …

New versatile approach for analysis of PEG content in conjugates and complexes with biomacromolecules based on FTIR spectroscopy.

IM Deygen, ЕV Kudryashova - Colloids and Surfaces B: Biointerfaces, 2016 - Elsevier
Here we report a new approach based on FTIR-spectroscopy for determining the degree of
PEGylation in biomolecules. We show that the PEG C single bondOsingle bondC peak (at …

Molecular dynamics simulation of small molecules interacting with biological membranes

C Martinotti, L Ruiz‐Perez, E Deplazes… - …, 2020 - Wiley Online Library
Cell membranes protect and compartmentalise cells and their organelles. The semi‐
permeable nature of these membranes controls the exchange of solutes across their …

Magnetic liposome design for drug release systems responsive to super-low frequency alternating current magnetic field (AC MF)

KY Vlasova, A Piroyan, IM Le-Deygen… - Journal of colloid and …, 2019 - Elsevier
Hypothesis Magnetic liposomes are shown to release the entrapped dye once modulated by
low frequency AC MF. The mechanism and effectiveness of MF application should depend …

NSAIDs interactions with membranes: a biophysical approach

C Nunes, G Brezesinski, C Pereira-Leite, JLFC Lima… - Langmuir, 2011 - ACS Publications
This work focuses on the interaction of four representative NSAIDs (nimesulide,
indomethacin, meloxicam, and piroxicam) with different membrane models (liposomes …

[HTML][HTML] Biophysical study of the non-steroidal anti-inflammatory drugs (NSAID) ibuprofen, naproxen and diclofenac with phosphatidylserine bilayer membranes

M Manrique-Moreno, L Heinbockel, M Suwalsky… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) represent an effective pain treatment option
and therefore one of the most sold therapeutic agents worldwide. The study of the molecular …

[HTML][HTML] Effects of NSAIDs on the nanoscopic dynamics of lipid membrane

VK Sharma, E Mamontov, M Tyagi - Biochimica et Biophysica Acta (BBA) …, 2020 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely prescribed for their antipyretic,
anti-inflammatory, and painkiller actions despite a wide spectrum of side effects. The …