Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative
disease that affects the central nervous system (CNS). MS is characterized by immune …

The excessive formation of reactive oxygen species (ROS) and impairment of defensive
antioxidant systems leads to a condition known as oxidative stress. The main source of free …

There are over 15 disease-modifying drugs that have been approved over the last 20 years
for the treatment of relapsing–remitting multiple sclerosis (MS), but there are limited …

Reactive oxygen species (ROS) molecules are implicated in signal transduction pathways
and thereby control a range of biological activities. Immune cells are constantly confronted …

The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …

The body of evidence from the past three decades demonstrates that oxidative stress can be
involved in several diseases. This study aims to summarise the current state of knowledge …

Oxidative stress (OS) disrupts the chemical integrity of macromolecules and increases the
risk of neurodegenerative diseases. Fisetin is a flavonoid that exhibits potent antioxidant …

Curcumin, the dietary polyphenol isolated from Curcuma longa (turmeric), is commonly used
as an herb and spice worldwide. Because of its bio-pharmacological effects curcumin is also …

Multiple roles have been indicated for reactive oxygen species (ROS) in the immune system
in recent years. ROS have been extensively studied due to their ability to damage DNA and …

Neurodegenerative diseases cause severe impairments in cognitive and motor function.
With an increasing aging population and the onset of these diseases between 50 and 70 …