Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Recent progress on small molecule-based fluorescent imaging probes for hypochlorous acid (HOCl)/hypochlorite (OCl−)

N Kwon, Y Chen, X Chen, MH Kim, J Yoon - Dyes and Pigments, 2022 - Elsevier
Reactive oxygen species (ROS) and nitrogen species (RNS) are very important in various
pathological and physiological processes. In particular, hypochlorous acid/hypochlorite …

[HTML][HTML] A hemicyanine-based fluorescent probe for ratiometric detection of ClO-and turn-on detection of viscosity and its imaging application in mitochondria of living …

SL Xu, FF Guo, ZH Xu, Y Wang, TD James - Sensors and Actuators B …, 2023 - Elsevier
A water-soluble fluorescent probe 1 based on chromene-hemicyanine has been developed,
that exhibits ratiometric fluorescent response toward hypochlorite (ClO-) with the LOD (0.082 …

Strategies to construct efficient singlet oxygen-generating photosensitizers

E Pang, S Zhao, B Wang, G Niu, X Song… - Coordination Chemistry …, 2022 - Elsevier
Abstract Singlet oxygen (1 O 2) generation is an essential function of photosensitizer (PS) as
applied to photodynamic therapy (PDT) of cancer. As illustrated in the Jablonski diagram …

Molecular Design of Highly Efficient Heavy-Atom-free NpImidazole Derivatives for Two-Photon Photodynamic Therapy and ClO Detection

W Cui, X Wei, J Guo, X Hao, LY Zou… - Journal of Chemical …, 2023 - ACS Publications
Two-photon photodynamic therapy (TP-PDT), as a treatment technology with deep
penetration and less damage, provides a broad prospect for cancer treatment. Nowadays …

Imidazolium-Based Heavy-Atom-Free Photosensitizer for Nucleus-Targeted Fluorescence Bioimaging and Photodynamic Therapy

TC Pham, TTH Hoang, DN Tran, G Kim… - … Applied Materials & …, 2023 - ACS Publications
The development of heavy-atom-free photosensitizers (PSs) for photodynamic therapy
(PDT) has encountered significant challenges in achieving simultaneous high fluorescence …

Site-selected thionated benzothioxanthene chromophores as heavy-atom-free small-molecule photosensitizers for photodynamic therapy

M Deiana, P Josse, C Dalinot, A Osmolovskyi… - Communications …, 2022 - nature.com
Photodynamic therapy is a clinically approved anticancer modality that employs a light-
activated agent (photosensitizer) to generate cytotoxic reactive oxygen species (ROS) …

Imidazole–carbazole conjugate for two-photon-excited photodynamic therapy and fluorescence bioimaging

TC Pham, DJ Lee, DH Kim, J Yoon… - Chemical …, 2023 - pubs.rsc.org
A heavy-atom-free photosensitizer (CI) based on an imidazole–carbazole conjugate
exhibited strong fluorescence emission and ROS generation via both type I and II …

A specifically triggered turn-on fluorescent probe platform and its visual imaging of HClO in cells, arthritis and tumors

XB Wang, HJ Li, Q Li, Y Ding, C Hu, YC Wu - Journal of Hazardous …, 2022 - Elsevier
Understanding disease-related processes at the molecular level is of great importance for
the prevention and treatment of diseases. However, due to the lack of effective analytical …

Engineering of an upconversion luminescence sensing platform based on the competition effect for mercury-ion monitoring in green tea

K Zhang, G Zhu, Y Wei, L Zhang… - Journal of Agricultural and …, 2021 - ACS Publications
Accurately monitoring mercury ions (Hg2+) in food and agriculture-related matrixes (eg,
green tea) is of great significance to safeguard food safety. Here, we employed …