Migraine affects more than one billion individuals each year across the world, and is one of
the most common neurologic disorders, with a high prevalence and morbidity, especially …

Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome …

Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria.
A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine …

After the emergence of a novel coronavirus named SARS‐CoV‐2, coronavirus disease 2019
(COVID‐19) was initially characterized by fever, sore throat, cough, and dyspnea, mainly …

Migraine affects over a billion individuals worldwide but its genetic underpinning remains
largely unknown. Here, we performed a genome-wide association study of 102,084 …

Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …

Sensitization of trigeminal ganglion neurons contributes to primary headache disorders such
as migraine, but the specific neuronal and non-neuronal trigeminal subtypes that are …

Background Neuroinflammation has an important role in the pathophysiology of migraine,
which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight …

The understanding of migraine pathophysiology is advancing rapidly. Improved
characterisation and diagnosis of its clinical features have led to the view of migraine as a …